Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7195717 | 1.00 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1MEN1KMT2ABLM | |
| SCHEMBL2162138 | 0.82 | MAPT (0.35) | ALDH1A1L3MBTL1MEN1KMT2AFAAH | |
| SCHEMBL4582755 | 0.74 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1MEN1KMT2AFAAH | |
| SCHEMBL9885900 | 0.69 | GPR84 (0.39) | FAAHMAPT | |
| SCHEMBL23901063 | 0.67 | MGLL (0.41) | KMT2AFAAHLMNAMAPT | |
| SCHEMBL21648859 | 0.67 | MGLL (0.41) | KMT2AFAAHLMNAMAPT | |
| SCHEMBL21575529 | 0.67 | MGLL (0.41) | KMT2AFAAHLMNAMAPT | |
| SCHEMBL23901147 | 0.67 | MGLL (0.41) | KMT2AFAAHLMNAMAPT | |
| SCHEMBL5145638 | 0.67 | OPRM1 (0.47) | MEN1KMT2ALMNAMAPT | |
| SCHEMBL14850646 | 0.66 | KMT2A (0.44) | ALDH1A1L3MBTL1MEN1KMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687282-B2 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-03-30 | — | — | US | disclosed |
| US-20070026384-A1 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-02-01 | — | — | US | disclosed |
| US-7115401-B2 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-10-03 | — | — | US | disclosed |
| US-6342379-B1 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070026384-A1 | Detection of transmembrane potentials by optical methods | MBOAT1, TRPM4, NME4 | ALDH1A1 2425/4885L3MBTL1 2291/4885MEN1 1020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.