Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | VCP | P55072 | 5/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26618063 | 1.00 | HTR1A (0.47) | HTR1AVCPUSP2MAPK1HSD17B10 | |
| SCHEMBL22466241 | 0.83 | HTR1A (0.49) | HTR1AVCPMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL23922990 | 0.79 | LMNA (0.49) | HTR1AUSP2MAPK1HSD17B10CYP1A2 | |
| SCHEMBL29858370 | 0.73 | ADRA2C (0.58) | HTR1AUSP2MAPK1HSD17B10CYP1A2 | |
| SCHEMBL20557842 | 0.73 | ADRA2C (0.58) | HTR1AUSP2MAPK1HSD17B10CYP1A2 | |
| SCHEMBL16400691 | 0.71 | MEN1 (0.51) | USP2MAPK1HSD17B10CYP1A2CYP2D6 | |
| SCHEMBL20159148 | 0.70 | KHK (0.45) | HTR1AVCPALDH1A1RIPK1HTR1D | |
| SCHEMBL31316092 | 0.69 | PDE4A (0.47) | HTR1AHTR2C | |
| SCHEMBL26646365 | 0.69 | PDE4A (0.47) | HTR1AHTR2C | |
| SCHEMBL16748956 | 0.69 | SIGMAR1 (0.44) | HTR1ACYP1A2TP53RIPK1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119451951-A | Compounds for inhibition of KIF18A | 沃拉斯查疗法公司 | 2025-02-14 | — | — | CN | disclosed |