SCHEMBL3143071

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29173918	0.84	SLC6A2 (0.46)	ALDH1A1HSD17B1HSD17B2LMNA
	SCHEMBL430659	0.83	ALDH1A1 (0.46)	ALDH1A1TSHRCYP3A4LMNA
	SCHEMBL430660	0.83	ALDH1A1 (0.46)	ALDH1A1TSHRCYP3A4LMNA
	SCHEMBL21518499	0.83	SLC6A2 (0.47)	ALDH1A1KDM4E
	SCHEMBL21518473	0.81	MTNR1A (0.50)	ALDH1A1HSD17B1HSD17B2ESR1
	SCHEMBL21518476	0.80	POLQ (0.45)	ALDH1A1CYP3A4KDM4E
	Hydrochloric Acid SCHEMBL14632491	0.77	PLAU (0.44)	—
	SCHEMBL28647276	0.77	ALDH1A1 (0.55)	ALDH1A1TSHRCYP3A4HSD17B1HSD17B2
	SCHEMBL21518496	0.76	SMN1; SMN2 (0.46)	ALDH1A1CYP3A4LMNAKIF11
	SCHEMBL3143698	0.76	SHBG (0.41)	ALDH1A1ESR1ACHELMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.