SCHEMBL29615610

SCHEMBL29615610

CC[C@H](C)[C@H](N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](C(=O)O)[C@@H](C)CC

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CTSD P07339 2/20 0.37
▸ ENPEP Q07075 5/20 0.36
▸ ANPEP P15144 2/20 0.36
▸ LNPEP Q9UIQ6 2/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ AKR1B1 P15121 1/20 0.36
▸ CA2 P00918 2/20 0.35
▸ CA1 P00915 1/20 0.35
▸ MME P08473 1/20 0.35
▸ ECE1 P42892 1/20 0.35
▸ FPR2 P25090 2/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20397486 0.94 ANPEP (0.40) CTSDENPEPANPEPLNPEP
SCHEMBL29691686 0.93 CTSD (0.38) CTSDENPEPALDH1A1AKR1B1CA2
SCHEMBL30356037 0.92 CTSB (0.40) CTSD
SCHEMBL31318666 0.92 ENPEP (0.41) ENPEPANPEPLNPEPMME
SCHEMBL15011306 0.90 ACE (0.42) MME
SCHEMBL15011307 0.90 ACE (0.42) MME
SCHEMBL30874984 0.90 ACE (0.42) MME
SCHEMBL30434077 0.89 CTSD (0.42) CTSD
SCHEMBL28101255 0.88 ACE (0.38) CTSDENPEPANPEPLNPEPMME
SCHEMBL31433276 0.88 ACE (0.39) MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146063-A1 CYCLIC CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2026-05-28 — — US disclosed
US-20260125426-A1 CYCLIC CELL-PENETRATING PEPTIDES AND USES THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2026-05-07 — — US disclosed
US-20260070947-A1 CYCLIC CELL-PENETRATING PEPTIDE COMPOUNDS OHIO STATE INNOVATION FOUNDATION (US) 2026-03-12 — — US disclosed
US-20260070948-A1 CYCLIC CELL-PENETRATING PEPTIDES WITH CARGO OHIO STATE INNOVATION FOUNDATION (US) 2026-03-12 — — US disclosed
US-20260008816-A1 CYCLIC CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2026-01-08 — — US disclosed
US-20260008812-A1 CELL-PENETRATING PEPTIDE COMPOUNDS OHIO STATE INNOVATION FOUNDATION (US) 2026-01-08 — — US disclosed
US-20260008813-A1 CELL-PENETRATING PEPTIDE COMPOUNDS OHIO STATE INNOVATION FOUNDATION (US) 2026-01-08 — — US disclosed
US-20260001916-A1 CYCLIC CELL-PENETRATING PEPTIDE COMPOUNDS OHIO STATE INNOVATION FOUNDATION (US) 2026-01-01 — — US disclosed
US-12454552-B2 Cyclic cell penetrating peptides comprising beta-hairpin motifs and methods of making and using thereof OHIO STATE INNOVATION FOUNDATION (US) 2025-10-28 — — US disclosed
US-20250243244-A1 CYCLIC CELL PENETRATING PEPTIDES ENTRADA THERAPEUTICS, INC. 2025-07-31 — — US disclosed
US-20240158445-A1 CYCLIC CELL-PENETRATING PEPTIDES WITH THREE OR MORE HYDROPHOBIC RESIDUES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-05-16 — — US disclosed
US-11976094-B2 Method for preparing peptides SULFOTOOLS GMBH (DE) 2024-05-07 — — US disclosed
US-11878046-B2 Di-sulfide containing cell penetrating peptides and methods of making and using thereof OHIO STATE INNOVATION FOUNDATION (US) 2024-01-23 — — US disclosed
US-20220306693-A1 CYCLIC CELL PENETRATING PEPTIDES COMPRISING BETA-HAIRPIN MOTIFS AND METHODS OF MAKING AND USING THEREOF OHIO STATE INNOVATION FOUNDATION 2022-09-29 — — US disclosed
US-20220220151-A1 METHOD FOR PREPARING PEPTIDES SULFOTOOLS GMBH (DE) 2022-07-14 — — US disclosed
US-20220177523-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF ENTRADA THERAPEUTICS, INC. 2022-06-09 — — US disclosed
US-11352394-B2 Cyclic cell penetrating peptides comprising beta-hairpin motifs and methods of making and using thereof OHIO STATE INNOVATION FOUNDATION (US) 2022-06-07 — — US disclosed
US-11351222-B2 Di-sulfide containing cell penetrating peptides and methods of making and using thereof OHIO STATE INNOVATION FOUNDATION (US) 2022-06-07 — — US disclosed
US-20220160819-A1 DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-05-26 — — US disclosed
US-11319340-B2 Method for preparing peptides SULFOTOOLS GMBH (DE) 2022-05-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (20 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11976094-B2 Method for preparing peptides VIP, DNPEP, PEPD CTSD 328/4885ENPEP 15/4885ANPEP 4/4885
US-11352394-B2 Cyclic cell penetrating peptides comprising beta-hairpin motifs and methods of making and using thereof VIP, LNPEP, IAPP CTSD 1024/4885ENPEP 49/4885ANPEP 12/4885
US-20260008816-A1 CYCLIC CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF SLC3A2, SPPL2B, SLC7A1 CTSD 352/4885ENPEP 124/4885ANPEP 88/4885
US-11878046-B2 Di-sulfide containing cell penetrating peptides and methods of making and using thereof IKBKE, IKBKB, SHARPIN CTSD 2411/4885ENPEP 855/4885ANPEP 863/4885
US-20250243244-A1 CYCLIC CELL PENETRATING PEPTIDES SLC47A1, SLC47A2, VIP CTSD 257/4885ENPEP 301/4885ANPEP 132/4885
US-20260008812-A1 CELL-PENETRATING PEPTIDE COMPOUNDS SLC38A7, SLC7A1, SLC6A7 CTSD 229/4885ENPEP 162/4885ANPEP 15/4885
US-20260146063-A1 CYCLIC CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF VIP, SLC7A1, SLC6A15 CTSD 860/4885ENPEP 175/4885ANPEP 16/4885
US-20220306693-A1 CYCLIC CELL PENETRATING PEPTIDES COMPRISING BETA-HAIRPIN MOTIFS AND METHODS OF MAKING AND USING THEREOF CHN2, TAP2, VIP CTSD 2046/4885ENPEP 187/4885ANPEP 53/4885
US-20260125426-A1 CYCLIC CELL-PENETRATING PEPTIDES AND USES THEREOF SLC7A1, TAP1, SLC7A5 CTSD 157/4885ENPEP 367/4885ANPEP 54/4885
US-20220177523-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF VIP, LNPEP, TAP1 CTSD 251/4885ENPEP 26/4885ANPEP 8/4885
US-20260070947-A1 CYCLIC CELL-PENETRATING PEPTIDE COMPOUNDS SLC7A1, SLC38A7, SLC6A19 CTSD 789/4885ENPEP 413/4885ANPEP 57/4885
US-20220160819-A1 DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF IKBKE, IKBKB, SHARPIN CTSD 2411/4885ENPEP 855/4885ANPEP 863/4885
US-20260070948-A1 CYCLIC CELL-PENETRATING PEPTIDES WITH CARGO SLC7A1, SLC38A7, SLC6A19 CTSD 1218/4885ENPEP 300/4885ANPEP 77/4885
US-11351222-B2 Di-sulfide containing cell penetrating peptides and methods of making and using thereof IKBKE, IKBKB, SHARPIN CTSD 2411/4885ENPEP 855/4885ANPEP 863/4885
US-20260001916-A1 CYCLIC CELL-PENETRATING PEPTIDE COMPOUNDS SLC7A1, SLC38A7, SLC6A19 CTSD 1102/4885ENPEP 190/4885ANPEP 36/4885
US-11319340-B2 Method for preparing peptides VIP, DNPEP, PEPD CTSD 350/4885ENPEP 14/4885ANPEP 4/4885
US-12454552-B2 Cyclic cell penetrating peptides comprising beta-hairpin motifs and methods of making and using thereof CHN2, TAP2, VIP CTSD 2046/4885ENPEP 187/4885ANPEP 53/4885
US-20260008813-A1 CELL-PENETRATING PEPTIDE COMPOUNDS SLC7A1, SLC38A7, SLC6A19 CTSD 250/4885ENPEP 173/4885ANPEP 18/4885
US-20240158445-A1 CYCLIC CELL-PENETRATING PEPTIDES WITH THREE OR MORE HYDROPHOBIC RESIDUES SLC3A2, SLC7A1, ARGLU1 CTSD 1203/4885ENPEP 172/4885ANPEP 45/4885
US-20220220151-A1 METHOD FOR PREPARING PEPTIDES VIP, DNPEP, PEPD CTSD 328/4885ENPEP 15/4885ANPEP 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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