SCHEMBL7964589

SCHEMBL7964589

Cc1nccn1Cc1ccc(Br)c(F)c1

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
KCNH2 Q12809 9/20 0.44
HTR1A P08908 1/20 0.44
HTR2C P28335 1/20 0.44
GRM2 Q14416 1/20 0.43
GRIN2B Q13224 1/20 0.41
ALDH1A1 P00352 1/20 0.38
POLB P06746 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26127200 0.85 LMNA (0.54) LMNAL3MBTL1KCNH2HTR1AHTR2C
SCHEMBL26130734 0.79 LMNA (0.48) LMNAL3MBTL1KCNH2HTR1AHTR2C
SCHEMBL7966541 0.79 LMNA (0.48) LMNAL3MBTL1KCNH2HTR1AHTR2C
SCHEMBL31270697 0.79 LMNA (0.74) LMNAL3MBTL1KCNH2HTR1AHTR2C
SCHEMBL17102309 0.78 LMNA (0.64) LMNAL3MBTL1KCNH2HTR1AHTR2C
SCHEMBL31729500 0.74 LMNA (0.68) LMNAL3MBTL1KCNH2HTR1AHTR2C
SCHEMBL169675 0.74 LMNA (0.68) LMNAL3MBTL1KCNH2HTR1AHTR2C
SCHEMBL23121198 0.74 LMNA (0.68) LMNAL3MBTL1KCNH2HTR1AHTR2C
SCHEMBL29700587 0.74 LMNA (0.68) LMNAL3MBTL1KCNH2HTR1AHTR2C
SCHEMBL29700592 0.73 KCNH2 (0.44) LMNAL3MBTL1KCNH2GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260028333-A1 NEW COMPOUNDS VICORE PHARMA AB (SE) 2026-01-29 US disclosed
US-12435072-B2 Compounds VICORE PHARMA AB (SE) 2025-10-07 US disclosed
US-20240174657-A1 SELECTIVE ANGIOTENSIN II RECEPTOR LIGANDS VICORE PHARMA AB (SE) 2024-05-30 US disclosed
EP-4313976-A1 SELECTIVE ANGIOTENSIN II RECEPTOR LIGANDS Vicore Pharma AB (SE) 2024-02-07 EP disclosed
US-20220388994-A1 NEW COMPOUNDS VICORE PHARMA AB (SE) 2022-12-08 US disclosed
WO-2022200786-A1 SELECTIVE ANGIOTENSIN II RECEPTOR LIGANDS VICORE PHARMA AB (SE) 2022-09-29 WO disclosed
EP-4031240-A1 NEW COMPOUNDS Vicore Pharma AB (SE) 2022-07-27 EP disclosed
CN-114786774-A Novel compounds 维科尔药物公司 2022-07-22 CN disclosed
WO-2021053344-A1 NEW COMPOUNDS VICORE PHARMA AB (SE) 2021-03-25 WO disclosed
US-6333335-B1 TO INHIBIT PRENYL-PROTEIN TRANSFERASE AND THE PRENYLATION OF THE ONCOGENE PROTEIN RAS MERCK & CO., INC. 2001-12-25 US disclosed
WO-2001007046-A1 PRENYL-PROTEIN TRANSFERASE INHIBITORS MERCK & CO., INC. (US) 2001-02-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028333-A1 NEW COMPOUNDS AGTR1, AGTR2, REN LMNA 1958/4885L3MBTL1 4556/4885KCNH2 1389/4885
US-20220388994-A1 NEW COMPOUNDS RXFP3, RXFP4, RXFP1 LMNA 3099/4885L3MBTL1 3046/4885KCNH2 1563/4885
US-20240174657-A1 SELECTIVE ANGIOTENSIN II RECEPTOR LIGANDS AGTR1, AGTR2, MSR1 LMNA 3605/4885L3MBTL1 4509/4885KCNH2 1188/4885
US-12435072-B2 Compounds RXFP3, RXFP4, ARG1 LMNA 2591/4885L3MBTL1 2822/4885KCNH2 1177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.