Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434752 | 0.84 | SLC5A2 (0.38) | ALDH1A1KDM4ENPC1RAB9AHPGD | |
| SCHEMBL31434754 | 0.84 | GABRA2 (0.45) | GABRA2GABRB2ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL754523 | 0.81 | ALDH1A1 (0.46) | GABRA2GABRB2ALDH1A1KDM4ENPC1 | |
| SCHEMBL31434561 | 0.80 | LMNA (0.46) | ALDH1A1L3MBTL1KDM4ENPC1RAB9A | |
| SCHEMBL31434844 | 0.80 | TP53 (0.48) | GABRA2GABRB2KDM4ENPC1RAB9A | |
| SCHEMBL31434610 | 0.80 | CYP1A2 (0.41) | GABRA2GABRB2ALDH1A1NPC1RAB9A | |
| SCHEMBL31434853 | 0.78 | MAPT (0.38) | ALDH1A1L3MBTL1KDM4ENPC1RAB9A | |
| SCHEMBL31434641 | 0.78 | GABRA2 (0.40) | GABRA2GABRB2ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL31434700 | 0.77 | CYP1A2 (0.37) | GABRA2GABRB2ALDH1A1KDM4ENPC1 | |
| SCHEMBL2817924 | 0.75 | HDAC1 (0.58) | GABRA2GABRB2ALDH1A1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085347-A1 | IL4I1 INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-04-24 | — | — | WO | disclosed |