SCHEMBL31435409

SCHEMBL31435409

O=C(O)c1cc(-n2cccn2)nc(-n2cccn2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.59
KDM4E B2RXH2 3/20 0.52
ALDH1A1 P00352 2/20 0.52
KMT2A Q03164 2/20 0.43
ADORA2A P29274 4/20 0.43
ADORA1 P30542 4/20 0.43
MEN1 O00255 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
G6PD P11413 1/20 0.43
BRD4 O60885 1/20 0.42
HTT P42858 1/20 0.42
KDM6B O15054 3/20 0.40
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
HIF1A Q16665 1/20 0.39
KDM5A P29375 2/20 0.39
KDM4C Q9H3R0 2/20 0.39
KDM5B Q9UGL1 2/20 0.39
KDM4A O75164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15974174 0.81 LMNA (0.63) LMNAKDM4EALDH1A1MAPTKDM6B
SCHEMBL31556398 0.77 LMNA (0.61) LMNAKDM4EALDH1A1KMT2AMEN1
SCHEMBL29425707 0.75 LMNA (1.00) LMNAKDM4EALDH1A1KMT2AMEN1
SCHEMBL322839 0.75 LMNA (1.00) LMNAKDM4EALDH1A1KMT2AMEN1
SCHEMBL20462873 0.73 KAT6A (0.54) LMNAMAPTKDM5AKDM4CKDM5B
SCHEMBL18311228 0.73 KAT6A (0.59) LMNAKDM5AKDM4CKDM5BKDM2B
SCHEMBL2462672 0.73 KDM4E (0.59) LMNAKDM4EALDH1A1KMT2AADORA2A
SCHEMBL405843 0.73 ALDH1A1 (0.59) LMNAKDM4EALDH1A1KMT2AADORA2A
SCHEMBL10027698 0.73 ALDH1A1 (0.59) LMNAKDM4EALDH1A1KMT2AADORA2A
SCHEMBL321724 0.73 LMNA (0.61) LMNAKDM4EALDH1A1MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025217208-A1 CHEMICAL MECHANICAL PLANARIZATION POLISHING FOR INTERCONNECTS DIFFUSION BARRIER MATERIALS VERSUM MATERIALS US, LLC (US) 2025-10-16 WO claimed
CN-119371460-A Octamolybdate metal organic complex and preparation method and application thereof 兴义民族师范学院 2025-01-28 CN claimed
CN-121045579-B Nickel-based metal organic framework, preparation method and detection application thereof 南京邮电大学 2026-01-27 CN disclosed
CN-121045579-A Nickel-based metal organic framework, preparation method and detection application thereof 南京邮电大学 2025-12-02 CN disclosed
WO-2025217208-A1 CHEMICAL MECHANICAL PLANARIZATION POLISHING FOR INTERCONNECTS DIFFUSION BARRIER MATERIALS VERSUM MATERIALS US, LLC (US) 2025-10-16 WO disclosed
CN-119371460-A Octamolybdate metal organic complex and preparation method and application thereof 兴义民族师范学院 2025-01-28 CN disclosed