Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | MC4R | P32245 | 2/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30752375 | 0.81 | BRD4 (0.33) | BRD4KDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL30752370 | 0.80 | BRD4 (0.32) | BRD4 | |
| SCHEMBL31438275 | 0.80 | REN (0.34) | HTR6KDM4EHSD17B10NR3C1PGR | |
| SCHEMBL31438250 | 0.79 | MET (0.38) | BRD4HTR6NR3C1PGRNR3C2 | |
| SCHEMBL31399832 | 0.77 | HTR6 (0.39) | HTR2CHTR6BDKRB2KDM4ENR3C1 | |
| SCHEMBL31438280 | 0.74 | IKBKE (0.36) | EDNRAADRA1DADRA1AADRA1B | |
| SCHEMBL31438271 | 0.74 | REN (0.33) | HTR6NR3C1PGRNR3C2AR | |
| SCHEMBL17850535 | 0.73 | TRIM24 (0.51) | HTR2AHTR6SMN1; SMN2NR3C1PGR | |
| SCHEMBL31438293 | 0.73 | HTR2C (0.34) | HTR2CHTR2AHTR6NR3C1PGR | |
| SCHEMBL27037001 | 0.70 | BRD4 (0.42) | BRD4HTR6GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585257-A | Novel 7-substituted indole sulfonamide derivatives | 豪夫迈·罗氏有限公司 | 2025-03-07 | — | — | CN | disclosed |