Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2012048 | 0.86 | HSD11B1 (0.51) | ALDH1A1MAPTHSD11B1GAATSHR | |
| SCHEMBL2003858 | 0.84 | ALDH1A1 (0.58) | ALDH1A1GAAALOX15TSHRGFER | |
| SCHEMBL2007089 | 0.80 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD11B1GAATSHR | |
| SCHEMBL2006369 | 0.80 | HSD11B1 (0.50) | MAPTHSD11B1 | |
| SCHEMBL4684441 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPTHSD11B1GAAALOX15 | |
| SCHEMBL4685416 | 0.78 | HSD11B1 (0.41) | MAPTHSD11B1 | |
| SCHEMBL3054414 | 0.78 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD11B1GAATSHR | |
| SCHEMBL2000970 | 0.77 | VCAM1 (0.42) | ALDH1A1MAPTLMNAHSD11B1GAA | |
| SCHEMBL3052047 | 0.77 | ALDH1A1 (0.40) | ALDH1A1HSD11B1GAATSHRNPSR1 | |
| SCHEMBL2009133 | 0.76 | HSD11B1 (0.49) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981504-B1 | THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURO DEGENERATIVE DISEASES | REMYND NV (BE) | 2010-07-21 | — | — | EP | claimed |