Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10950638 | 0.80 | POLB (0.44) | POLBALOX15KDM4EMEN1MAPT | |
| SCHEMBL30142954 | 0.80 | SMN1; SMN2 (0.41) | POLBALOX15KDM4EMEN1MAPT | |
| SCHEMBL11019559 | 0.77 | LMNA (0.51) | POLBMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL9578027 | 0.77 | POLB (0.42) | POLBALOX15KDM4EMEN1MAPT | |
| SCHEMBL5934973 | 0.77 | CYP3A4 (0.44) | POLBALOX15KDM4EMEN1MAPT | |
| SCHEMBL19307390 | 0.76 | FFAR3 (0.47) | POLBMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL301061 | 0.76 | FFAR3 (0.47) | POLBMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL28857096 | 0.76 | MEN1 (0.48) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5107238 | 0.75 | OPRM1 (0.41) | POLBALOX15KDM4EMEN1MAPT | |
| SCHEMBL30932975 | 0.74 | FFAR3 (0.45) | POLBMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7847041-B2 | Cobalt-catalyzed asymmetric cyclopropanation of electron-deficient olefins | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-12-07 | — | — | US | disclosed |
| US-20100076239-A1 | ASYMMETRIC CYCLOPROPANATION OF ELECTRON-DEFICIENT OLEFINS WITH DIAZO REAGENTS | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-03-25 | — | — | US | disclosed |
| US-20090069519-A1 | COBALT-CATALYZED ASYMMETRIC CYCLOPROPANATION OF ELECTRON-DEFICIENT OLEFINS | NATIONAL SCIENCE FOUNDATION | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076239-A1 | ASYMMETRIC CYCLOPROPANATION OF ELECTRON-DEFICIENT OLEFINS WITH DIAZO REAGENTS | DUOX2, DUOX1, PPOX | POLB 1397/4885ALOX15 120/4885KDM4E 2600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.