SCHEMBL3144356

SCHEMBL3144356

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nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
ALDH1A1 P00352 2/20 0.36
TDP1 Q9NUW8 3/20 0.36
CYP3A4 P08684 1/20 0.35
HCAR2 Q8TDS4 3/20 0.33
SERPINE1 P05121 1/20 0.33
ATM Q13315 1/20 0.33
NAAA Q02083 1/20 0.32
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
LMNA P02545 1/20 0.31
RAD52 P43351 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3109285 0.94 TSHR (0.43) TSHRALDH1A1TDP1CYP3A4HCAR2
SCHEMBL27855347 0.91 TSHR (0.46) TSHRALDH1A1TDP1CYP3A4HCAR2
SCHEMBL3099499 0.91 TSHR (0.46) TSHRALDH1A1TDP1CYP3A4HCAR2
SCHEMBL34343 0.87 THRB (0.37) TSHRALDH1A1TDP1
SCHEMBL10952662 0.86 CAMK2A (0.38) TSHRALDH1A1TDP1CYP3A4HCAR2
SCHEMBL1948952 0.84 ALDH1A1 (0.58) TSHRALDH1A1TDP1HCAR2ATM
SCHEMBL27379280 0.84 ACHE (0.41) TSHRALDH1A1TDP1CYP3A4HCAR2
SCHEMBL1401947 0.84 ALDH1A1 (0.58) TSHRALDH1A1TDP1HCAR2ATM
Hydrochloric Acid SCHEMBL10892981 0.82 ALDH1A1 (0.56) TSHRALDH1A1TDP1HCAR2ATM
SCHEMBL1401944 0.82 ALDH1A1 (0.56) TSHRALDH1A1TDP1HCAR2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111568-A1 LUMATEPERONE AND ANALOGUES, AS 5-HT2A OR 5-HT2A/D2 RECEPTOR MODULATORS, FOR USE IN THE TREATMENT OF PSYCHIATRIC DISORDERS CAUSED BY VIRAL, BACTERIAL, OR AUTOIMMUNE ENCEPHALITIS, AND OF PSYCHIATRIC SYMPTOMS THEREOF INTRA-CELLULAR THERAPIES, INC. (US) 2025-05-30 WO disclosed
EP-4525874-A1 NOVEL METHODS Intra-Cellular Therapies, Inc. (US) 2025-03-26 EP disclosed
EP-4493560-A2 ORGANIC COMPOUNDS Intra-Cellular Therapies, Inc. (US) 2025-01-22 EP disclosed
WO-2023225620-A1 NOVEL METHODS INTRA-CELLULAR THERAPIES, INC. (US) 2023-11-23 WO disclosed
WO-2023178111-A2 ORGANIC COMPOUNDS INTRA-CELLULAR THERAPIES, INC. (US) 2023-09-21 WO disclosed
EP-4072554-A1 ORGANIC COMPOUND Intra-Cellular Therapies, Inc. (US) 2022-10-19 EP disclosed
WO-2021119334-A1 ORGANIC COMPOUND INTRA-CELLULAR THERAPIES, INC. (US) 2021-06-17 WO disclosed
EP-3768271-A1 ORGANIC COMPOUNDS Intra-Cellular Therapies, Inc. (US) 2021-01-27 EP disclosed
EP-3768254-A1 ORGANIC COMPOUNDS Intra-Cellular Therapies, Inc. (US) 2021-01-27 EP disclosed
US-10632079-B2 Microspheres having core/shell structure OTSUKA PHARMACEUTICALS CO., LTD. (JP) 2020-04-28 US disclosed
EP-1418887-A1 HEPARIN STENT Zoucas Kirurgkonsult AB (SE) 2004-05-19 EP disclosed
US-20040052854-A1 Porous substances and methods for producing the same TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-03-18 US disclosed
EP-1023044-B1 APATITE-COATED SOLID COMPOSITION TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2004-02-04 EP disclosed
EP-1354581-A1 POROUS SUBSTANCE AND PROCESS FOR PRODUCING THE SAME Takeda Chemical Industries, Ltd. (JP) 2003-10-22 EP disclosed
WO-2003011250-A1 HEPARIN STENT ZOUCAS KIRURGKONSULT AB (SE) 2003-02-13 WO disclosed
EP-1251902-A1 MEDICAL DEVICE Zoucas Kirurgkonsult AB (SE) 2002-10-30 EP disclosed
WO-2001056646-A1 MEDICAL DEVICE ZOUCAS KIRURGKONSULT AB (SE) 2001-08-09 WO disclosed
EP-0353961-B1 Thermoplastic elastomer-based low vulnerability ammunition gun propellants THIOKOL CORP (US) 1995-12-27 EP disclosed
US-4919737-A NON-CROSSLINKED, RESIDUE-FREE BINDER CONTAINING AMORPHOUS POLYETHER AND CRYSTALLINE POLYESTER BLOCKS MORTON THIOKOL INC. (US) 1990-04-24 US disclosed
EP-0353961-A2 Thermoplastic elastomer-based low vulnerability ammunition gun propellants THIOKOL CORPORATION (US) 1990-02-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040052854-A1 Porous substances and methods for producing the same PGF, TACR1, CA3 TSHR 2307/4885ALDH1A1 2293/4885TDP1 3466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.