Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | FABP2 | P12104 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15645990 | 0.82 | CES2 (0.47) | AKR1C3AKR1C2PTGS1PTGS2MEN1 | |
| SCHEMBL15645912 | 0.82 | CES2 (0.47) | AKR1C3AKR1C2PTGS1PTGS2MEN1 | |
| SCHEMBL16267366 | 0.81 | CXCL8 (0.42) | RIPK1AKR1C3AKR1C2PTGS1PTGS2 | |
| SCHEMBL807528 | 0.79 | TSHR (0.39) | RIPK1TSHRL3MBTL1CYP2C9HPGD | |
| SCHEMBL31445554 | 0.78 | KMT2A (0.44) | AKR1C3AKR1C2PTGS1PTGS2KMT2A | |
| SCHEMBL11139560 | 0.75 | CXCL8 (0.45) | RIPK1AKR1C3AKR1C2PTGS1PTGS2 | |
| SCHEMBL31561697 | 0.73 | L3MBTL1 (0.45) | PTGS1PTGS2LMNATSHRSLC22A6 | |
| SCHEMBL7050570 | 0.73 | L3MBTL1 (0.45) | PTGS1PTGS2LMNATSHRSLC22A6 | |
| SCHEMBL11153493 | 0.72 | AKR1C3 (0.56) | AKR1C3AKR1C2PTGS1PTGS2MEN1 | |
| SCHEMBL20534709 | 0.72 | KMT2A (0.47) | AKR1C3AKR1C2PTGS1PTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |