Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | PDE4A | P27815 | 2/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5566870 | 1.00 | PTPN1 (0.54) | PTPN1PDE4APDE3APTGS1SNCA | |
| SCHEMBL13271762 | 1.00 | PTPN1 (0.54) | PTPN1PDE4APDE3APTGS1SNCA | |
| SCHEMBL5561100 | 1.00 | PTPN1 (0.54) | PTPN1PDE4APDE3APTGS1SNCA | |
| SCHEMBL6449202 | 1.00 | PTPN1 (0.54) | PTPN1PDE4APDE3APTGS1SNCA | |
| SCHEMBL5562750 | 0.85 | PTPN1 (0.46) | PTPN1PDE4APDE3APTGS1SNCA | |
| SCHEMBL3132944 | 0.85 | PTPN1 (0.46) | PTPN1PDE4APDE3APTGS1SNCA | |
| SCHEMBL3132937 | 0.85 | PTPN1 (0.46) | PTPN1PDE4APDE3APTGS1SNCA | |
| SCHEMBL27660726 | 0.84 | PTPN1 (0.55) | PTPN1PDE4APDE3APTGS1SNCA | |
| SCHEMBL2138789 | 0.84 | PTPN1 (0.55) | PTPN1PDE4APDE3APTGS1SNCA | |
| SCHEMBL13597513 | 0.84 | PTPN1 (0.55) | PTPN1PDE4APDE3APTGS1SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583753-B1 | PROCESS FOR THE MANUFACTURE OF ALPHA-TOCOPHERYL ACETATE | DSM IP ASSETS BV (NL) | 2010-07-21 | — | — | EP | claimed |
| EP-1562929-B1 | MANUFACTURE OF TOCOPHERYL ACETATE | DSM IP ASSETS BV (NL) | 2007-11-14 | — | — | EP | claimed |
| US-20070112206-A1 | Manufacture of tocopheryl acetate | BONRATH WERNER | 2007-05-17 | — | — | US | claimed |
| US-7169943-B2 | Manufacture of tocopheryl acetate | DSM IP ASSETS B.V. (NL) | 2007-01-30 | — | — | US | claimed |
| US-7135580-B2 | Process for the manufacture of α-tocopheryl acetate | DSM IP ASSETS B.V. (NL) | 2006-11-14 | — | — | US | claimed |
| US-20060094886-A1 | Catalytic reaction of alkylation with sulfur containing compound esterification and hydrogenation after ring closure | DSM IP ASSETS B.V. (NL) | 2006-05-04 | — | — | US | claimed |
| US-20060052618-A1 | Process for the manufacture of alpha-tocopheryl acetate | DSM ASSETS B.V. (NL) | 2006-03-09 | — | — | US | claimed |
| EP-1562929-A1 | MANUFACTURE OF TOCOPHERYL ACETATE | DSM IP Assets B.V. (NL) | 2005-08-17 | — | — | EP | claimed |
| WO-2004046126-A1 | MANUFACTURE OF TOCOPHERYL ACETATE | DSM IP ASSETS B.V. (NL) | 2004-06-03 | — | — | WO | claimed |
| EP-1583753-B1 | PROCESS FOR THE MANUFACTURE OF ALPHA-TOCOPHERYL ACETATE | DSM IP ASSETS BV (NL) | 2010-07-21 | — | — | EP | disclosed |
| EP-1562929-B1 | MANUFACTURE OF TOCOPHERYL ACETATE | DSM IP ASSETS BV (NL) | 2007-11-14 | — | — | EP | disclosed |
| CN-100344621-C | Process for the manufacture of alpha-tocopheryl acetate | DSM IP ASSETS BV (NL) | 2007-10-24 | — | — | CN | disclosed |
| US-20070112206-A1 | Manufacture of tocopheryl acetate | BONRATH WERNER | 2007-05-17 | — | — | US | disclosed |
| US-20070112206-A1 | Manufacture of tocopheryl acetate | BONRATH WERNER | 2007-05-17 | — | — | US | disclosed |
| US-20060052618-A1 | Process for the manufacture of alpha-tocopheryl acetate | DSM ASSETS B.V. (NL) | 2006-03-09 | — | — | US | disclosed |
| US-20060052618-A1 | Process for the manufacture of alpha-tocopheryl acetate | DSM ASSETS B.V. (NL) | 2006-03-09 | — | — | US | disclosed |
| EP-1583753-A1 | PROCESS FOR THE MANUFACTURE OF ALPHA-TOCOPHERYL ACETATE | DSM IP Assets B.V. (NL) | 2005-10-12 | — | — | EP | disclosed |
| EP-1562929-A1 | MANUFACTURE OF TOCOPHERYL ACETATE | DSM IP Assets B.V. (NL) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004063182-A1 | PROCESS FOR THE MANUFACTURE OF α-TOCOPHERYL ACETATE | DSM IP ASSETS B.V. (NL) | 2004-07-29 | — | — | WO | disclosed |
| WO-2004046126-A1 | MANUFACTURE OF TOCOPHERYL ACETATE | DSM IP ASSETS B.V. (NL) | 2004-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112206-A1 | Manufacture of tocopheryl acetate | TTPA, VKORC1L1, NR1H2 | PTPN1 3831/4885PDE4A 1449/4885PDE3A 1261/4885 |
| US-20060094886-A1 | Catalytic reaction of alkylation with sulfur containing compound esterification and hydrogenation after ring closure | TTPA, VKORC1L1, GSTO1 | PTPN1 4558/4885PDE4A 1926/4885PDE3A 2208/4885 |
| US-20060052618-A1 | Process for the manufacture of alpha-tocopheryl acetate | ELOVL3, CYP4F3, COXFA4 | PTPN1 4618/4885PDE4A 4098/4885PDE3A 3495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.