Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.37 |
| ▸ | TTPA | P49638 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13597513 | 1.00 | PTPN1 (0.55) | PTPN1PTGS1PDE4ASNCAPDE3A | |
| SCHEMBL27660726 | 1.00 | PTPN1 (0.55) | PTPN1PTGS1PDE4ASNCAPDE3A | |
| SCHEMBL3276137 | 1.00 | PTPN1 (0.55) | PTPN1PTGS1PDE4ASNCAPDE3A | |
| SCHEMBL13384946 | 0.88 | IMPDH2 (0.47) | PTPN1PTGS1PDE4ASNCAPDE3A | |
| SCHEMBL869358 | 0.86 | PTGS1 (0.57) | PTPN1PTGS1PDE4ASNCAPDE3A | |
| SCHEMBL29357300 | 0.86 | PTGS1 (0.57) | PTPN1PTGS1PDE4ASNCAPDE3A | |
| SCHEMBL28023376 | 0.86 | PTGS1 (0.57) | PTPN1PTGS1PDE4ASNCAPDE3A | |
| SCHEMBL29474878 | 0.86 | PTGS1 (0.57) | PTPN1PTGS1PDE4ASNCAPDE3A | |
| SCHEMBL5566870 | 0.84 | PTPN1 (0.54) | PTPN1PTGS1PDE4ASNCAPDE3A | |
| SCHEMBL3144740 | 0.84 | PTPN1 (0.54) | PTPN1PTGS1PDE4ASNCAPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7626046-B2 | Isolated, purified phytyltrimethylhydroquinone is cyclized to alpha-tocopherol with use of acid catalyst such as sulfuric acid, phosphoric acid, a polyperfluoroalkylenesulphonic acid, a heteropoly acid, zinc chloride, boron trifluoride, aluminium trichloride, or a mixture | DSM IP ASSETS B.V. (NL) | 2009-12-01 | — | — | US | claimed |
| EP-1583753-A1 | PROCESS FOR THE MANUFACTURE OF ALPHA-TOCOPHERYL ACETATE | DSM IP Assets B.V. (NL) | 2005-10-12 | — | — | EP | claimed |
| US-20050187393-A1 | Isolated, purified phytyltrimethylhydroquinone is cyclized to alpha-tocopherol with use of acid catalyst such as sulfuric acid, phosphoric acid, a polyperfluoroalkylenesulphonic acid, a heteropoly acid, zinc chloride, boron trifluoride, aluminium trichloride, or a mixture | DSM IP ASSETS B.V. (NL) | 2005-08-25 | — | — | US | claimed |
| EP-1562929-A1 | MANUFACTURE OF TOCOPHERYL ACETATE | DSM IP Assets B.V. (NL) | 2005-08-17 | — | — | EP | claimed |
| EP-1446398-B1 | MANUFACTURE OF ALPHA- TOCOPHEROL | DSM IP ASSETS BV (NL) | 2005-04-13 | — | — | EP | claimed |
| EP-1446398-A1 | MANUFACTURE OF ALPHA- TOCOPHEROL | DSM IP Assets B.V. (NL) | 2004-08-18 | — | — | EP | claimed |
| WO-2004063182-A1 | PROCESS FOR THE MANUFACTURE OF α-TOCOPHERYL ACETATE | DSM IP ASSETS B.V. (NL) | 2004-07-29 | — | — | WO | claimed |
| WO-2004046126-A1 | MANUFACTURE OF TOCOPHERYL ACETATE | DSM IP ASSETS B.V. (NL) | 2004-06-03 | — | — | WO | claimed |
| WO-2003037883-A1 | MANUFACTURE OF ALPHA- TOCOPHEROL | DSM IP ASSETS B.V. (NL) | 2003-05-08 | — | — | WO | claimed |
| EP-3652162-B1 | NOVEL SYNTHESIS OF INTERMEDIATES FOR THE PREPARATION OF ALPHA-TOCOPHEROL | DSM IP ASSETS BV (NL) | 2023-02-22 | — | — | EP | disclosed |
| US-8664264-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2014-03-04 | — | — | US | disclosed |
| EP-1778661-B1 | PROCESS FOR THE MANUFACTURE OF CHROMAN DERIVATIVES, ESPECIALLY ALPHA-TOCOPHEROL AND ALKANOATES THEREOF | DSM IP ASSETS BV (NL) | 2014-01-22 | — | — | EP | disclosed |
| US-8431727-B2 | Process for the manufacture of chroman derivatives, especially α-tocopherol and alka-noates thereof | DSM ASSETS B.V. (NL) | 2013-04-30 | — | — | US | disclosed |
| US-8431727-B2 | Process for the manufacture of chroman derivatives, especially α-tocopherol and alka-noates thereof | DSM ASSETS B.V. (NL) | 2013-04-30 | — | — | US | disclosed |
| WO-2003037883-A1 | MANUFACTURE OF ALPHA- TOCOPHEROL | DSM IP ASSETS B.V. (NL) | 2003-05-08 | — | — | WO | disclosed |
| WO-2003037883-A1 | MANUFACTURE OF ALPHA- TOCOPHEROL | DSM IP ASSETS B.V. (NL) | 2003-05-08 | — | — | WO | disclosed |
| EP-1254130-A4 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RES DEV FOUNDATION (US) | 2003-04-23 | — | — | EP | disclosed |
| EP-1254130-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 2002-11-06 | — | — | EP | disclosed |
| US-20020107207-A1 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION | 2002-08-08 | — | — | US | disclosed |
| WO-2001058889-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 2001-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187393-A1 | Isolated, purified phytyltrimethylhydroquinone is cyclized to alpha-tocopherol with use of acid catalyst such as sulfuric acid, phosphoric acid, a polyperfluoroalkylenesulphonic acid, a heteropoly acid, zinc chloride, boron trifluoride, aluminium trichloride, or a mixture | TTPA, ROR1, RORC | PTPN1 2192/4885PTGS1 2175/4885PDE4A 4780/4885 |
| US-20020107207-A1 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | TST, HCCS, TXNRD3 | PTPN1 2209/4885PTGS1 131/4885PDE4A 4783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.