Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31453580 | 0.84 | MAPT (0.42) | KDM4EALDH1A1KMT2AMDM2 | |
| SCHEMBL31453611 | 0.75 | NR4A1 (0.35) | ALDH1A1SLC6A4SLC6A2SLC6A3POLB | |
| SCHEMBL31453578 | 0.71 | MAPT (0.43) | ALDH1A1KMT2AMDM2NPC1RAB9A | |
| SCHEMBL5175912 | 0.71 | LMNA (0.49) | KDM4EALDH1A1POLBKMT2ANR4A1 | |
| SCHEMBL4022487 | 0.71 | LMNA (0.49) | KDM4EALDH1A1POLBKMT2ANR4A1 | |
| SCHEMBL5175922 | 0.71 | LMNA (0.49) | KDM4EALDH1A1POLBKMT2ANR4A1 | |
| SCHEMBL4212119 | 0.71 | AKR1C3 (0.52) | KDM4EALDH1A1POLBTDP1KMT2A | |
| SCHEMBL1164367 | 0.70 | HSD17B1 (0.49) | KDM4EALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL31453570 | 0.69 | MAPT (0.41) | ALDH1A1KMT2AMDM2 | |
| SCHEMBL31453677 | 0.67 | ALDH1A1 (0.45) | ALDH1A1POLBKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025016138-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | SUZHOU EOC MEDICAL RESEARCH CO., LTD. (CN) | 2025-01-23 | — | — | WO | disclosed |