Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15564665 | 0.79 | CYP2C9 (0.48) | CYP2C9CYP2C19GRIN1GRIN2BCTSL | |
| SCHEMBL1809933 | 0.78 | CTSL (0.45) | CYP2C9CYP2C19TAAR1LMNAGRIN1 | |
| SCHEMBL9403491 | 0.73 | TSHR (0.39) | TAAR1LMNATSHRCTSLCTSB | |
| SCHEMBL3387736 | 0.72 | TAAR1 (0.38) | TAAR1LMNATSHRCTSLCTSB | |
| SCHEMBL582586 | 0.72 | TSHR (0.44) | TAAR1LMNATSHRCTSLCTSB | |
| SCHEMBL1625947 | 0.72 | LMNA (0.39) | CYP2C9CYP2C19TAAR1LMNAGRIN1 | |
| SCHEMBL1625944 | 0.72 | LMNA (0.39) | CYP2C9CYP2C19TAAR1LMNAGRIN1 | |
| SCHEMBL784898 | 0.72 | CYP2C9 (0.47) | CYP2C9CYP2C19TSHRCTSLCTSB | |
| SCHEMBL9982226 | 0.71 | CYP2C9 (0.39) | CYP2C9CYP2C19LMNATSHRPOLB | |
| SCHEMBL16612546 | 0.71 | OPRM1 (0.40) | CYP2C9CYP2C19GRIN2BOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |