Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455512 | 0.94 | CYP17A1 (0.45) | CYP17A1NAMPTSUV39H2DRD2SYK | |
| SCHEMBL31455132 | 0.80 | CYP17A1 (0.42) | CYP17A1NAMPTDRD2NPC1RAB9A | |
| SCHEMBL23899088 | 0.79 | NAMPT (0.53) | CYP17A1NAMPTDRD2AURKARPS6KB1 | |
| SCHEMBL28664086 | 0.78 | CYP17A1 (0.47) | CYP17A1NAMPTDRD2SYKNPC1 | |
| SCHEMBL17605464 | 0.78 | BCHE (0.42) | HDAC1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL31455379 | 0.78 | DRD2 (0.43) | CYP17A1NAMPTDRD2NPC1RAB9A | |
| SCHEMBL31455557 | 0.78 | JAK2 (0.42) | CYP17A1NAMPTDRD2PTGDR2MAPK14 | |
| SCHEMBL3641906 | 0.78 | KMT2A (0.47) | RAB9AALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL17606417 | 0.77 | SSTR3 (0.46) | RAB9AHDAC1ALDH1A1MEN1KMT2A | |
| SCHEMBL17606418 | 0.77 | SSTR3 (0.46) | RAB9AHDAC1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |