Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.36 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455557 | 0.83 | JAK2 (0.42) | CYP17A1MEN1KMT2AMMP1MMP2 | |
| SCHEMBL31455379 | 0.81 | DRD2 (0.43) | CYP17A1DRD2BCL2BECN1PPARG | |
| SCHEMBL31455183 | 0.80 | CYP17A1 (0.46) | CYP17A1MEN1KMT2ADRD2NPC1 | |
| SCHEMBL31455524 | 0.79 | ALDH1A1 (0.39) | MEN1KMT2AMAPT | |
| SCHEMBL28664086 | 0.75 | CYP17A1 (0.47) | CYP17A1DRD2NPC1RAB9ANAMPT | |
| SCHEMBL31455512 | 0.75 | CYP17A1 (0.45) | CYP17A1MEN1KMT2ADRD2BCL2 | |
| SCHEMBL27178925 | 0.74 | EPHX2 (0.45) | CYP17A1GPR119 | |
| SCHEMBL1543215 | 0.72 | ALDH1A1 (0.51) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL13240737 | 0.72 | ALDH1A1 (0.51) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL22930812 | 0.72 | CYP17A1 (0.57) | CYP17A1MMP1MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |