Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | LYN | P07948 | 1/20 | 0.37 |
| ▸ | HCK | P08631 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | FRK | P42685 | 1/20 | 0.37 |
| ▸ | BLK | P51451 | 1/20 | 0.37 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455132 | 0.83 | CYP17A1 (0.42) | CYP17A1MMP1MMP2MMP9MMP8 | |
| SCHEMBL31455379 | 0.83 | DRD2 (0.43) | CYP17A1DRD2LCKFYNLYN | |
| SCHEMBL31455031 | 0.79 | HRH4 (0.38) | JAK2JAK1LTA4H | |
| SCHEMBL31455512 | 0.79 | CYP17A1 (0.45) | CYP17A1DRD2MEN1KMT2APTGDR2 | |
| SCHEMBL31455183 | 0.78 | CYP17A1 (0.46) | CYP17A1DRD2MEN1KMT2APTGDR2 | |
| SCHEMBL22930812 | 0.75 | CYP17A1 (0.57) | CYP17A1MMP1MMP2MMP9MMP8 | |
| SCHEMBL30872826 | 0.73 | CYP17A1 (0.52) | CYP17A1MMP1MMP2MMP9MMP8 | |
| SCHEMBL28664086 | 0.72 | CYP17A1 (0.47) | CYP17A1DRD2NAMPT | |
| SCHEMBL8949097 | 0.71 | ALDH1A1 (0.50) | JAK2JAK1MEN1KMT2A | |
| SCHEMBL25928005 | 0.71 | ALDH1A1 (0.50) | JAK2JAK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |