Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | LYN | P07948 | 1/20 | 0.37 |
| ▸ | HCK | P08631 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | FRK | P42685 | 1/20 | 0.37 |
| ▸ | BLK | P51451 | 1/20 | 0.37 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455557 | 0.83 | JAK2 (0.42) | DRD2CYP17A1NAMPTLCKFYN | |
| SCHEMBL31455132 | 0.81 | CYP17A1 (0.42) | DRD2CYP17A1NAMPTNPC1RAB9A | |
| SCHEMBL31455533 | 0.79 | ALDH1A1 (0.39) | SMN1; SMN2 | |
| SCHEMBL31455183 | 0.78 | CYP17A1 (0.46) | DRD2CYP17A1NAMPTNPC1RAB9A | |
| SCHEMBL28664086 | 0.75 | CYP17A1 (0.47) | DRD2CYP17A1NAMPTNPC1RAB9A | |
| SCHEMBL31455512 | 0.75 | CYP17A1 (0.45) | DRD2CYP17A1NAMPTPTGDR2MAPK14 | |
| SCHEMBL27178925 | 0.74 | EPHX2 (0.45) | CYP17A1TSHRPTPN2PTPN1PTPN6 | |
| SCHEMBL10028043 | 0.71 | DRD2 (0.48) | DRD2CYP17A1HRH3NAMPTPTGDR2 | |
| SCHEMBL23899088 | 0.71 | NAMPT (0.53) | DRD2CYP17A1NAMPTPTPN2PTPN1 | |
| SCHEMBL16246084 | 0.71 | CYP17A1 (0.58) | DRD2CYP17A1NAMPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |