Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455183 | 0.94 | CYP17A1 (0.46) | CYP17A1NAMPTSUV39H2DRD2SYK | |
| SCHEMBL31455557 | 0.79 | JAK2 (0.42) | CYP17A1NAMPTDRD2PTGDR2MAPK14 | |
| SCHEMBL23899088 | 0.78 | NAMPT (0.53) | CYP17A1NAMPTDRD2EPHX2AURKA | |
| SCHEMBL31629934 | 0.78 | POLB (0.51) | MEN1LMNAKMT2A | |
| SCHEMBL2370551 | 0.78 | LTA4H (0.48) | MAPTMEN1LMNAKMT2A | |
| SCHEMBL2370547 | 0.78 | LTA4H (0.48) | MAPTMEN1LMNAKMT2A | |
| SCHEMBL31455132 | 0.75 | CYP17A1 (0.42) | CYP17A1NAMPTDRD2PTGDR2MAPK14 | |
| SCHEMBL31455379 | 0.75 | DRD2 (0.43) | CYP17A1NAMPTDRD2PTGDR2MAPK14 | |
| SCHEMBL28664086 | 0.75 | CYP17A1 (0.47) | CYP17A1NAMPTDRD2SYKMAPKAPK2 | |
| SCHEMBL30842059 | 0.74 | NPC1 (0.47) | EPHX2MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |