Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455244 | 0.87 | CYP2C9 (0.43) | SIGMAR1CYP2D6CYP2C9BCHEACHE | |
| SCHEMBL31455328 | 0.85 | DRD4 (0.44) | SIGMAR1BCHEACHEJAK2SYK | |
| SCHEMBL27227252 | 0.83 | SIGMAR1 (0.52) | SIGMAR1MAPK1BCHEACHETMEM97 | |
| SCHEMBL30802383 | 0.83 | SIGMAR1 (0.52) | SIGMAR1MAPK1BCHEACHETMEM97 | |
| SCHEMBL27226835 | 0.81 | SIGMAR1 (0.46) | SIGMAR1MAPK1TMEM97MEN1KMT2A | |
| SCHEMBL30802389 | 0.81 | SIGMAR1 (0.46) | SIGMAR1MAPK1TMEM97MEN1KMT2A | |
| SCHEMBL30802461 | 0.79 | JAK2 (0.44) | CYP2C9JAK2SYKFAAH | |
| SCHEMBL27225984 | 0.79 | JAK2 (0.44) | CYP2C9JAK2SYKFAAH | |
| SCHEMBL31455394 | 0.78 | MAPT (0.36) | JAK2SYK | |
| SCHEMBL31455312 | 0.77 | LTA4H (0.45) | JAK2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |