Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455311 | 0.86 | DRD2 (0.46) | DRD4DRD2ACHESIGMAR1POLB | |
| SCHEMBL31455198 | 0.85 | SIGMAR1 (0.41) | ACHEFAAHSIGMAR1BCHEJAK2 | |
| SCHEMBL30802383 | 0.84 | SIGMAR1 (0.52) | DRD4DRD2ACHESIGMAR1BCHE | |
| SCHEMBL27227252 | 0.84 | SIGMAR1 (0.52) | DRD4DRD2ACHESIGMAR1BCHE | |
| SCHEMBL30802389 | 0.82 | SIGMAR1 (0.46) | DRD4SIGMAR1 | |
| SCHEMBL27226835 | 0.82 | SIGMAR1 (0.46) | DRD4SIGMAR1 | |
| SCHEMBL27225984 | 0.80 | JAK2 (0.44) | FAAHJAK2SYK | |
| SCHEMBL30802461 | 0.80 | JAK2 (0.44) | FAAHJAK2SYK | |
| SCHEMBL31455312 | 0.79 | LTA4H (0.45) | JAK2SYK | |
| SCHEMBL31455394 | 0.78 | MAPT (0.36) | JAK2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |