Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455198 | 0.87 | SIGMAR1 (0.41) | CYP2C9CYP2D6BCHEACHESIGMAR1 | |
| SCHEMBL31455311 | 0.84 | DRD2 (0.46) | BCHEACHESIGMAR1JAK2SYK | |
| SCHEMBL31455090 | 0.76 | LTA4H (0.47) | JAK2SYKGAAMAPTHPGD | |
| SCHEMBL31455293 | 0.73 | AKT1 (0.59) | CYP2C9CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL31455206 | 0.72 | CHRM2 (0.38) | JAK2SYKMCHR1 | |
| SCHEMBL31455328 | 0.71 | DRD4 (0.44) | BCHEACHESIGMAR1JAK2SYK | |
| SCHEMBL31455169 | 0.71 | ABCG2 (0.61) | KDM4EGAAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL31455366 | 0.70 | ALDH1A1 (0.61) | TSHRKDM4EMAPTHPGDHTT | |
| SCHEMBL31455172 | 0.70 | LTA4H (0.36) | CYP2D6JAK2CYP2C19MCHR1MAPT | |
| SCHEMBL6750641 | 0.70 | OPRM1 (0.54) | CYP2C9CYP2D6BCHEACHESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |