Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PTGFR | P43088 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455497 | 0.81 | ABCB1 (0.43) | MAPTBACE1 | |
| SCHEMBL31455383 | 0.77 | MAPT (0.43) | MAPTLMNANPC1RAB9AKDM4E | |
| SCHEMBL16179175 | 0.76 | LMNA (0.39) | IDO1MAPTEGFRLMNANPC1 | |
| SCHEMBL31455855 | 0.75 | IDO1 (0.45) | IDO1MAPTEGFRLMNANPC1 | |
| SCHEMBL28797575 | 0.75 | RGS12 (0.42) | BACE1LMNANPC1RAB9AKDM4E | |
| SCHEMBL30875970 | 0.74 | NOS3 (0.48) | MAPTLMNAGAAKDM4ETSHR | |
| SCHEMBL539616 | 0.74 | NOS3 (0.48) | MAPTLMNAGAAKDM4ETSHR | |
| SCHEMBL11971050 | 0.73 | ROCK1 (0.54) | IDO1EGFRMEN1KMT2A | |
| SCHEMBL14247759 | 0.72 | MAPK1 (0.53) | IDO1MAPTLMNANPC1RAB9A | |
| SCHEMBL27853621 | 0.72 | OPRM1 (0.49) | MAPTBACE1NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |