Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 7/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455383 | 0.85 | MAPT (0.43) | MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL31455200 | 0.81 | IDO1 (0.39) | MAPTBACE1 | |
| SCHEMBL31420324 | 0.80 | ABCG2 (0.40) | ABCC1MAPTMYCSMN1; SMN2L3MBTL1 | |
| SCHEMBL31455840 | 0.75 | ABCB1 (0.52) | ABCB1ABCC1MAPTMYCSMN1; SMN2 | |
| SCHEMBL31455065 | 0.74 | ABCB1 (0.44) | ABCB1ABCC1KCNMA1AKR1B10AKR1B1 | |
| SCHEMBL15940303 | 0.73 | APP (0.48) | ABCB1ABCC1MAPTAPPMYC | |
| SCHEMBL18104290 | 0.71 | L3MBTL1 (0.55) | ABCB1ABCC1MAPTAPPMYC | |
| SCHEMBL539616 | 0.71 | NOS3 (0.48) | MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL30875970 | 0.71 | NOS3 (0.48) | MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6573413 | 0.70 | ABCB1 (0.50) | ABCB1ABCC1APPKCNMA1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |