SCHEMBL31455266

SCHEMBL31455266

CC(C)(C)OC(=O)N1CC(c2ccc(Nc3cc(Br)ccc3[N+](=O)[O-])cc2)C1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
USP30 Q70CQ3 2/20 0.41
FPR2 P25090 6/20 0.41
FPR3 P25089 2/20 0.39
RORC P51449 2/20 0.39
NAMPT P43490 1/20 0.39
PDE4B Q07343 3/20 0.37
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
MKNK1 Q9BUB5 1/20 0.37
BACE1 P56817 1/20 0.36
IGF1R P08069 1/20 0.36
SLC34A1 Q06495 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31454988 0.82 MAPK1 (0.43) FPR2MAPTMKNK1SLC34A1
SCHEMBL31455504 0.82 MKNK1 (0.40) FPR2NAMPTALDH1A1LMNAMAPT
SCHEMBL15342504 0.82 USP30 (0.45) USP30FPR2FPR3RORCALDH1A1
SCHEMBL31455531 0.82 GPR119 (0.43) NAMPTALDH1A1LMNAMAPT
SCHEMBL30273842 0.81 MAPT (0.44) USP30RORCNAMPTPDE4BALDH1A1
SCHEMBL31237115 0.79 NAMPT (0.50) USP30NAMPTALDH1A1MAPTIGF1R
SCHEMBL31144715 0.78 PRMT1 (0.46) ALDH1A1LMNAMAPT
SCHEMBL15187965 0.77 RORC (0.56) USP30FPR2FPR3RORCNAMPT
SCHEMBL31455485 0.77 ALDH1A1 (0.44) USP30RORCPDE4BALDH1A1LMNA
SCHEMBL25273382 0.77 FPR2 (0.47) USP30FPR2FPR3ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025059577-A1 SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS ATAVISTIK BIO, INC. (US) 2025-03-20 WO disclosed