Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 4/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31420326 | 0.85 | NAMPT (0.40) | JAK3LCKBTKGPR119NAMPT | |
| SCHEMBL31455683 | 0.84 | JAK2 (0.46) | JAK3LCKBTKJAK2PTK2 | |
| SCHEMBL31454988 | 0.83 | MAPK1 (0.43) | MKNK1JAK3LCKBTKGPR119 | |
| SCHEMBL31455508 | 0.83 | MEN1 (0.39) | MKNK1JAK3LCKBTKGPR119 | |
| SCHEMBL31455266 | 0.82 | USP30 (0.41) | MKNK1ALDH1A1MAPTNAMPTIGF1R | |
| SCHEMBL31455299 | 0.80 | SLC34A1 (0.40) | JAK3LCKBTKNAMPTIGF1R | |
| SCHEMBL31455102 | 0.79 | NAMPT (0.45) | JAK3LCKBTKGPR119NAMPT | |
| SCHEMBL31144608 | 0.79 | NR1H2 (0.53) | MKNK1JAK3MAPTRAB9AIGF1R | |
| SCHEMBL10256994 | 0.79 | JAK1 (0.42) | MKNK1JAK3LCKBTKGPR119 | |
| SCHEMBL31455378 | 0.79 | HPGDS (0.44) | JAK3LCKBTKGPR119NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |