Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455623 | 0.94 | ALDH1A1 (0.53) | ALDH1A1KDM4EHDAC1HDAC2TDP1 | |
| SCHEMBL31455017 | 0.88 | ALDH1A1 (0.48) | ALDH1A1KDM4EHDAC1HDAC2TDP1 | |
| SCHEMBL31455342 | 0.85 | ALDH1A1 (0.57) | ALDH1A1KDM4ETDP1MAPTTSHR | |
| SCHEMBL31455090 | 0.81 | LTA4H (0.47) | ALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL31455642 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1MAPTTSHR | |
| SCHEMBL31455409 | 0.78 | ALDH1A1 (0.75) | ALDH1A1KDM4ETDP1MAPTTSHR | |
| SCHEMBL31455172 | 0.77 | LTA4H (0.36) | ALDH1A1HDAC1HDAC2TDP1MAPT | |
| SCHEMBL31455364 | 0.75 | ADORA1 (0.42) | HDAC1HDAC2MAPTKMT2AHTT | |
| SCHEMBL25385310 | 0.74 | ABCG2 (0.61) | ALDH1A1KDM4EMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL31455169 | 0.74 | ABCG2 (0.61) | ALDH1A1KDM4EMAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |