Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1730549 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10ATM | |
| SCHEMBL8922678 | 0.90 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10ATM | |
| SCHEMBL6644845 | 0.87 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10ATM | |
| SCHEMBL642243 | 0.84 | HCAR3 (0.53) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL6647697 | 0.84 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10ATM | |
| SCHEMBL29771091 | 0.83 | HRH3 (0.48) | KDM4EALDH1A1HSD17B10MAPTHCAR3 | |
| SCHEMBL820141 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10ATM | |
| SCHEMBL29699657 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10ATM | |
| SCHEMBL1730827 | 0.79 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL1018113 | 0.79 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |