SCHEMBL3145664

SCHEMBL3145664

CC1=Cc2cccc(-c3cc(C(C)C)cc(C(C)C)c3)c2C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20165781 0.81 BRD9 (0.35)
SCHEMBL27970546 0.78 HTR1A (0.42)
SCHEMBL3154256 0.77 PDCD1 (0.38)
SCHEMBL27500689 0.77 KDR (0.38)
SCHEMBL3150842 0.76 GSTP1 (0.42)
SCHEMBL30230061 0.76 GSTP1 (0.42)
SCHEMBL14142022 0.76 PTAFR (0.36)
SCHEMBL3159359 0.76 METAP2 (0.40)
SCHEMBL29776124 0.75 HTR1A (0.46)
SCHEMBL3145652 0.73 AKR1C3 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2935295-B1 CATALYST BOREALIS AG (AT) 2018-02-07 EP disclosed
EP-1270614-B1 Copolymers containing propylene and alpha-olefin comonomer BASELL POLYOLEFINE GMBH (DE) 2010-01-27 EP disclosed
US-6787618-B1 TRANSPARENT, STIFF MOLDING MATERIALS; IMPACT TOUGHNESS; FOOD PACKAGING BASELL POLYPROPYLEN GMBH (DE) 2004-09-07 US disclosed
EP-0776913-B1 High molecular weight copolymers BASELL POLYOLEFINE GMBH (DE) 2004-02-04 EP disclosed
EP-1270614-A2 Copolymers containing propylene and alpha-olefin comonomer Basell Polyolefine GmbH (DE) 2003-01-02 EP disclosed
US-6057408-A CATALYTIC ADDITION COPOLYMERIZATION OF PROPYLENE WITH ETHYLENE OR OLEFIN TARGOR GMBH (DE) 2000-05-02 US disclosed
EP-0776913-A2 High molecular weight copolymers HOECHST AKTIENGESELLSCHAFT (DE) 1997-06-04 EP disclosed