SCHEMBL27970546

SCHEMBL27970546

CC1=Cc2cccc(-c3cc(F)cc(F)c3)c2C1

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 2/20 0.42
HTR7 P34969 2/20 0.42
PIK3CD O00329 1/20 0.38
PIK3CA P42336 1/20 0.38
PIK3CB P42338 1/20 0.38
DRD2 P14416 1/20 0.33
DRD1 P21728 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20165781 0.83 BRD9 (0.35) HTR1A
SCHEMBL29776124 0.80 HTR1A (0.46) HTR1AHTR7
SCHEMBL27500689 0.80 KDR (0.38)
SCHEMBL3154256 0.80 PDCD1 (0.38) HTR1AHTR7
SCHEMBL14142022 0.78 PTAFR (0.36) HTR1AHTR7
SCHEMBL3145664 0.78
SCHEMBL20125003 0.77 ACHE (0.34) DRD2
SCHEMBL28896777 0.75 HTR1A (0.43) HTR1AHTR7PIK3CDPIK3CAPIK3CB
SCHEMBL30230061 0.75 GSTP1 (0.42)
SCHEMBL3150842 0.75 GSTP1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102627707-B Fluorinated ligand-containing metallocene catalyst and preparation method thereof SUZHOU APAC PHARMACEUTICAL TECHNOLOGY CO LTD 2014-08-13 CN disclosed