Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31457046 | 1.00 | KIF11 (0.46) | KIF11GRM5KDM4ETAAR1NPC1 | |
| SCHEMBL21542305 | 0.84 | KIF11 (0.56) | KIF11GRM5KDM4ETAAR1NPC1 | |
| SCHEMBL27374825 | 0.81 | LOXL2 (0.44) | KDM4ETAAR1L3MBTL1KMT2ALOXL2 | |
| SCHEMBL31456993 | 0.81 | LOXL2 (0.44) | KDM4ETAAR1L3MBTL1KMT2ALOXL2 | |
| SCHEMBL27374802 | 0.81 | HSD17B10 (0.43) | KDM4ETAAR1NPC1RAB9AL3MBTL1 | |
| SCHEMBL31457034 | 0.81 | HSD17B10 (0.43) | KDM4ETAAR1NPC1RAB9AL3MBTL1 | |
| SCHEMBL27703418 | 0.78 | CHRNB2 (0.52) | KIF11GRM5KDM4ELMNA | |
| SCHEMBL6088034 | 0.76 | KDM4E (0.64) | KIF11KDM4ETAAR1KMT2AGAA | |
| SCHEMBL31456969 | 0.76 | LOXL2 (0.48) | TAAR1KMT2ALOXL2MEN1 | |
| SCHEMBL27374959 | 0.76 | LOXL2 (0.48) | TAAR1KMT2ALOXL2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030000-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 넥스트젠바이오사이언스 | 2024-02-08 | — | — | WO | disclosed |