Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HNF4A | P41235 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31459970 | 0.86 | ALDH1A1 (0.42) | ALDH1A1TSHRSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL31460256 | 0.77 | METAP2 (0.33) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL17868978 | 0.77 | TSHR (0.43) | PPARGPPARATSHRHIF1ASMN1; SMN2 | |
| SCHEMBL31460434 | 0.77 | GAA (0.34) | ALDH1A1TSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL31460203 | 0.73 | CYP2C19 (0.32) | TSHRCYP2C19 | |
| SCHEMBL30706927 | 0.71 | NR4A3 (0.44) | ALDH1A1PPARGTSHRHIF1ASMN1; SMN2 | |
| SCHEMBL28943217 | 0.71 | USP2 (0.41) | GLAALDH1A1PPARGPPARAPTPN1 | |
| SCHEMBL31459997 | 0.67 | JUN (0.38) | GLAALDH1A1TSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL15885982 | 0.65 | NAMPT (0.49) | ALDH1A1L3MBTL1 | |
| SCHEMBL17869011 | 0.64 | MAPT (0.45) | ALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677749-A | Azaquinazoline pan KRAS inhibitors | 米拉蒂治疗股份有限公司 | 2025-03-21 | — | — | CN | disclosed |