SCHEMBL31461007

SCHEMBL31461007

N#Cc1ccc(Cl)c(S(=O)(=O)Cl)c1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 3/20 0.56
VCAM1 P19320 1/20 0.47
RAD51 Q06609 2/20 0.45
SLC22A12 Q96S37 5/20 0.43
PTGES2 Q9H7Z7 2/20 0.42
HSD11B1 P28845 1/20 0.40
FLT1 P17948 1/20 0.39
FLT4 P35916 1/20 0.39
KDR P35968 1/20 0.39
AKR1C3 P42330 1/20 0.39
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
S100A9 P06702 1/20 0.36
PDK1 Q15118 1/20 0.36
PDK2 Q15119 1/20 0.36
PDK3 Q15120 1/20 0.36
PDK4 Q16654 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1942524 1.00 TRPV4 (0.56) TRPV4VCAM1RAD51SLC22A12PTGES2
SCHEMBL29948706 0.85 TRPV4 (0.60) TRPV4VCAM1RAD51SLC22A12PTGES2
SCHEMBL1020883 0.85 TRPV4 (0.60) TRPV4VCAM1RAD51SLC22A12PTGES2
SCHEMBL6559198 0.83 PTGES2 (0.53) TRPV4VCAM1RAD51SLC22A12PTGES2
SCHEMBL12560333 0.83 VCAM1 (0.46) TRPV4VCAM1RAD51SLC22A12PTGES2
SCHEMBL27818431 0.82 TRPV4 (0.38) TRPV4VCAM1SLC22A12
SCHEMBL3079216 0.79 TRPV4 (0.54) TRPV4RAD51
SCHEMBL3071018 0.79 TRPV4 (0.58) TRPV4VCAM1RAD51SLC22A12HSD11B1
SCHEMBL11720000 0.79 GSTO1 (0.51) TRPV4VCAM1RAD51SLC22A12HSD11B1
SCHEMBL7532971 0.78 TRPV4 (0.53) TRPV4VCAM1RAD51HSD11B1FLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025101500-A1 METHODS FOR GENERATING EXTRACELLULAR VESICLES LOADED WITH RESOLVINS OHIO STATE INNOVATION FOUNDATION (US) 2025-05-15 WO disclosed