Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31461675 | 0.88 | RAB9A (0.46) | HPGDTP53GLAPOLBALDH1A1 | |
| SCHEMBL31461742 | 0.81 | RAB9A (0.38) | POLBALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL31461687 | 0.71 | HPGD (0.43) | HPGDTP53GLAPOLBALDH1A1 | |
| SCHEMBL31461654 | 0.69 | SMN1; SMN2 (0.43) | POLBALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL31461652 | 0.69 | KDM4E (0.49) | HPGDTP53GLAALDH1A1MAPT | |
| SCHEMBL27604453 | 0.67 | HPGD (1.00) | HPGDTP53GLAPOLBALDH1A1 | |
| SCHEMBL31461728 | 0.67 | SMN1; SMN2 (0.43) | HPGDTP53GLAALDH1A1MAPT | |
| SCHEMBL31461691 | 0.67 | PDE10A (0.44) | HPGDTP53GLAPOLBALDH1A1 | |
| SCHEMBL31461688 | 0.67 | PDE10A (0.44) | HPGDTP53GLAPOLBALDH1A1 | |
| SCHEMBL15686112 | 0.65 | HPGD (0.83) | HPGDTP53GLAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024543-A1 | TRICYCLIC UBE2K MODULATORS AND METHODS FOR THEIR USE | BPGBIO, INC. (US) | 2025-01-30 | — | — | WO | disclosed |