Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31461742 | 0.92 | RAB9A (0.38) | RAB9ANPC1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL31461655 | 0.88 | HPGD (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL31461654 | 0.82 | SMN1; SMN2 (0.43) | RAB9ANPC1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL31461687 | 0.78 | HPGD (0.43) | RAB9ANPC1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL26601373 | 0.78 | NPC1 (0.40) | RAB9ANPC1SMN1; SMN2ALDH1A1HDAC3 | |
| SCHEMBL31461688 | 0.78 | PDE10A (0.44) | RAB9ANPC1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL31461691 | 0.78 | PDE10A (0.44) | RAB9ANPC1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL31461728 | 0.78 | SMN1; SMN2 (0.43) | RAB9ANPC1SMN1; SMN2ALDH1A1HDAC3 | |
| SCHEMBL31461695 | 0.75 | TP53 (0.41) | RAB9ANPC1SMN1; SMN2ALDH1A1HDAC1 | |
| SCHEMBL31676173 | 0.74 | NPC1 (0.36) | RAB9ANPC1ALDH1A1POLBHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024543-A1 | TRICYCLIC UBE2K MODULATORS AND METHODS FOR THEIR USE | BPGBIO, INC. (US) | 2025-01-30 | — | — | WO | disclosed |