Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26601315 | 0.90 | BRAF (0.40) | ADORA3BRAFMAPK8MAPK10KDM4E | |
| SCHEMBL31461661 | 0.88 | EGLN1 (0.39) | BRAFF2REGFRBTKOPRM1 | |
| SCHEMBL31461718 | 0.82 | HCN1 (0.42) | KDM4EF2REGFRBTKMEN1 | |
| SCHEMBL31461716 | 0.80 | SLC6A9 (0.39) | MAPK8MAPK10F2REGFRBTK | |
| SCHEMBL31461667 | 0.80 | ALDH1A1 (0.42) | KDM4EF2REGFRBTK | |
| SCHEMBL31461717 | 0.80 | EGFR (0.42) | KDM4EF2REGFRBTK | |
| SCHEMBL30623744 | 0.80 | ALDH1A1 (0.40) | KDM4EF2REGFRBTKOPRM1 | |
| SCHEMBL26629778 | 0.80 | ALDH1A1 (0.40) | KDM4EF2REGFRBTKOPRM1 | |
| SCHEMBL31461693 | 0.80 | ALDH1A1 (0.44) | KDM4EF2REGFRBTKMEN1 | |
| SCHEMBL31461720 | 0.79 | HCN1 (0.41) | KDM4EF2REGFRBTKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024543-A1 | TRICYCLIC UBE2K MODULATORS AND METHODS FOR THEIR USE | BPGBIO, INC. (US) | 2025-01-30 | — | — | WO | disclosed |