Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31461687 | 0.82 | HPGD (0.43) | TP53SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL31461691 | 0.81 | PDE10A (0.44) | TP53SMN1; SMN2HDAC1NPC1RAB9A | |
| SCHEMBL31461688 | 0.81 | PDE10A (0.44) | TP53SMN1; SMN2HDAC1NPC1RAB9A | |
| SCHEMBL31461728 | 0.81 | SMN1; SMN2 (0.43) | TP53SMN1; SMN2HDAC1NPC1TSHR | |
| SCHEMBL31461675 | 0.75 | RAB9A (0.46) | TP53SMN1; SMN2HDAC1NPC1RAB9A | |
| SCHEMBL31461724 | 0.74 | HDAC1 (0.41) | TP53SMN1; SMN2HDAC1CNR2TSHR | |
| SCHEMBL31461652 | 0.71 | KDM4E (0.49) | TP53KDM4EALDH1A1HPGD | |
| SCHEMBL31461742 | 0.68 | RAB9A (0.38) | SMN1; SMN2HDAC1NPC1RAB9AKDM4E | |
| SCHEMBL31461694 | 0.65 | RAB9A (0.44) | TP53SMN1; SMN2HDAC1NPC1RAB9A | |
| SCHEMBL31461704 | 0.65 | RAB9A (0.44) | TP53SMN1; SMN2HDAC1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024543-A1 | TRICYCLIC UBE2K MODULATORS AND METHODS FOR THEIR USE | BPGBIO, INC. (US) | 2025-01-30 | — | — | WO | disclosed |