Water

Water

SCHEMBL3146475

NCl.O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL1925758 1.00
Hydrochloric Acid SCHEMBL27383561 0.89
Water SCHEMBL7268286 0.89
Water SCHEMBL28276463 0.89
Water SCHEMBL28011831 0.89
Water SCHEMBL28356694 0.89
SCHEMBL8757 0.87
SCHEMBL11367292 0.87
SCHEMBL906180 0.87
Water SCHEMBL5311502 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109164151-A A kind of CoNiO of trace detection copper ion2The method of nanometer-material-modified glass-carbon electrode 石河子大学 2019-01-08 CN claimed
CN-105112468-B A kind of method of multienzyme couple system preparation Chiral Amine 厦门大学 2019-01-08 CN claimed
CN-105063010-B A kind of multi-enzyme system and preparation method thereof of polyethyleneimine metal coordination immobilization 厦门大学 2018-08-10 CN claimed
US-4018628-A Process for coloring aluminium SWISS ALUMINIUM LTD. (CH) 1977-04-19 US claimed
CN-110872230-B Preparation method of 1- (trifluoromethyl) cyclopropane-1-carboxylic acid compound and intermediate thereof 浙江九洲药业股份有限公司 2023-07-28 CN disclosed
CN-110872230-A Preparation method and intermediate of 1- (trifluoromethyl) cyclopropane-1-carboxylic acid compound 浙江九洲药业股份有限公司 2020-03-10 CN disclosed
CN-104288103-B The method for being used to prepare the bioactive compound of nanoparticulate form 伊休蒂卡有限公司 2019-10-15 CN disclosed
CN-109884147-A A kind of electrochemical method of walnut shell base Carbon Materials modified glassy carbon electrode detection trace heavy metal 石河子大学 2019-06-14 CN disclosed
CN-109231239-A A method of ammonium chloride being recycled in the waste liquid that magnesium fluoride generates from preparing 湖南有色氟化学科技发展有限公司 2019-01-18 CN disclosed
CN-105112468-B A kind of method of multienzyme couple system preparation Chiral Amine 厦门大学 2019-01-08 CN disclosed
CN-109135689-A Completion fluid pH buffer and preparation method thereof 中国石油集团渤海钻探工程有限公司 2019-01-04 CN disclosed
CN-108993442-A A kind of preparation method of the molecular imprinted polymer on surface with high-adsorption-capacity 上海理工大学 2018-12-14 CN disclosed
US-4968774-A WRINKLE RESISTANCE SOCIETE FRANCAISE HOECHST (FR) 1990-11-06 US disclosed
CN-1009090-B Preparation method of compound capable of resisting cancer and relieving pain WANG YUBU (CN) 1990-08-08 CN disclosed
US-4778792-A Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders LABORATORIES NEGMA (FR) 1988-10-18 US disclosed
CN-86103115-A A kind of energy is anticancer, analgesic compound and method for making and purposes 1987-11-11 CN disclosed
US-4574059-A PHOSGENATION OF DIAMINE FORMED FROM HYDROGENATION AND HYDROGENOLYSIS OF 1,2-DIAZA-1,5,9-CYCLODODECADIENE ATOCHEM (FR) 1986-03-04 US disclosed
EP-0027242-B1 POLYMERIC ULTRAVIOLET ABSORBERS, PHOTOGRAPHIC MATERIAL INCLUDING THEM, AND PROCESS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-01-02 EP disclosed
US-4173706-A REACTING WITH MOLYBDENUM HEXAFLUORIDE INSTITUTE NATIONAL DE RECHERCHE CHIMIQUE APPLIQUEE (FR) 1979-11-06 US disclosed
US-4018628-A Process for coloring aluminium SWISS ALUMINIUM LTD. (CH) 1977-04-19 US disclosed