SCHEMBL31465417

SCHEMBL31465417

Nc1ccc(Oc2cccnc2C(=O)O)cc1F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
CYP3A4 P08684 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
BLM P54132 1/20 0.40
AGER Q15109 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
FEN1 P39748 2/20 0.39
CARM1 Q86X55 2/20 0.39
PRMT6 Q96LA8 1/20 0.39
PYGL P06737 4/20 0.38
PYGM P11217 3/20 0.38
GCK P35557 2/20 0.38
PARP10 Q53GL7 1/20 0.37
KMT2A Q03164 1/20 0.36
CYP1A2 P05177 1/20 0.36
MET P08581 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27711531 0.90 SMN1; SMN2 (0.44) KDM4EMAPTFEN1CARM1PRMT6
SCHEMBL28026579 0.85 GCK (0.44) CARM1PRMT6PYGLPYGMGCK
SCHEMBL30438344 0.85 GCK (0.44) CARM1PRMT6PYGLPYGMGCK
SCHEMBL27648431 0.82 KDR (0.39) KDM4EFEN1CARM1PRMT6PYGL
SCHEMBL2424045 0.82 KMT2A (0.48) KDM4EALDH1A1MAPTCYP3A4ALOX15
SCHEMBL28536955 0.78 PYGL (0.50) KDM4EALDH1A1TSHRBLML3MBTL1
SCHEMBL7052917 0.77 ALDH1A1 (0.52) KDM4EALDH1A1MAPTCYP3A4ALOX15
SCHEMBL10712243 0.75 RAB9A (0.51) KDM4EALDH1A1MAPTCYP3A4ALOX15
SCHEMBL28695841 0.74 TLR7 (0.46) KDM4EALDH1A1MAPTCYP3A4ALOX15
SCHEMBL8786186 0.74 ALDH1A1 (0.48) KDM4EALDH1A1MAPTCYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119667011-A Method for measuring compound 四川科伦药物研究院有限公司 2025-03-21 CN claimed
CN-119667011-A Method for measuring compound 四川科伦药物研究院有限公司 2025-03-21 CN disclosed