SCHEMBL31465682

SCHEMBL31465682

Cc1cccc(C)c1NC(=O)C(=O)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.53
CES1 P23141 1/20 0.53
RAB9A P51151 4/20 0.48
NPC1 O15118 3/20 0.48
MEN1 O00255 2/20 0.48
MAPT P10636 2/20 0.48
KMT2A Q03164 2/20 0.48
LMNA P02545 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.47
ALDH1A1 P00352 1/20 0.47
HTT P42858 1/20 0.47
TRPV1 Q8NER1 3/20 0.45
GAA P10253 1/20 0.45
S1PR4 O95977 1/20 0.43
PTGS1 P23219 1/20 0.43
KDM4E B2RXH2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9525322 0.86 NPC1 (0.59) RAB9ANPC1MEN1MAPTKMT2A
SCHEMBL31465697 0.83 RAB9A (0.44) CES2CES1RAB9ANPC1MEN1
SCHEMBL13647658 0.78 GAA (0.60) RAB9ANPC1MEN1MAPTKMT2A
SCHEMBL31465694 0.77 CES2 (0.55) CES2CES1RAB9ANPC1MEN1
SCHEMBL15775220 0.74 KDM4E (0.58) RAB9ANPC1MEN1MAPTKMT2A
SCHEMBL6430240 0.74 ALDH1A1 (0.70) RAB9ANPC1MEN1MAPTKMT2A
SCHEMBL31465687 0.73 ALDH1A1 (0.59) RAB9AMEN1MAPTKMT2ALMNA
SCHEMBL3924697 0.73 GAA (0.62) RAB9ANPC1MEN1MAPTKMT2A
SCHEMBL29268631 0.72 CES2 (0.62) CES2CES1TRPV1PTGS1
SCHEMBL13885541 0.72 GAA (0.74) RAB9ANPC1MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025056724-A1 IMINOAMIDE-TYPE COMPOUNDS AS LIGANDS FOR COPPER-CATALYZED COUPLING REACTIONS OF (HETERO)ARYL HALIDES BAYER AKTIENGESELLSCHAFT (DE) 2025-03-20 WO disclosed