Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31491366 | 0.76 | KIF11 (0.39) | KIF11SMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL7906240 | 0.75 | MEN1 (0.42) | SMN1; SMN2NPC1RAB9AMAPTPDE4B | |
| SCHEMBL19624259 | 0.75 | NFKB1 (0.51) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL375687 | 0.75 | PDE4B (0.44) | SMN1; SMN2RAB9AMAPTPDE4BPDE4D | |
| SCHEMBL31469077 | 0.75 | SYK (0.41) | SMN1; SMN2RAB9AMAPTMEN1KMT2A | |
| SCHEMBL3938216 | 0.74 | RHOA (0.46) | NPC1RAB9AMAPTPDE4BPDE4D | |
| SCHEMBL29056205 | 0.73 | PDE4B (0.50) | PDE4BPDE4DKDM4ESYK | |
| SCHEMBL30542633 | 0.73 | PDE4B (0.50) | PDE4BPDE4DKDM4ESYK | |
| SCHEMBL31469083 | 0.73 | PDE4B (0.47) | PDE4BPDE4D | |
| SCHEMBL13211477 | 0.73 | HPGD (0.46) | SMN1; SMN2NPC1RAB9AMAPTPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067168-A1 | AZA FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州爱科百发生物医药技术有限公司 | 2025-04-03 | — | — | WO | disclosed |