Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.40 |
| ▸ | LPL | P06858 | 2/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26104184 | 0.89 | LPL (0.42) | LIPGLPLDGAT1 | |
| SCHEMBL31469347 | 0.77 | LPL (0.39) | LIPGLPLDGAT1F11KEAP1 | |
| SCHEMBL31469360 | 0.76 | DGAT1 (0.36) | DGAT1F11KEAP1NFE2L2 | |
| SCHEMBL27265704 | 0.74 | LIPG (0.39) | LIPGLPLDGAT1KEAP1NFE2L2 | |
| SCHEMBL17426081 | 0.74 | NPC1 (0.38) | LIPGLPL | |
| SCHEMBL9948523 | 0.74 | ERBB2 (0.37) | DGAT1F11KEAP1NFE2L2 | |
| SCHEMBL26453177 | 0.72 | LPL (0.33) | LIPGLPLDGAT1F11 | |
| SCHEMBL23294581 | 0.71 | UCHL1 (0.36) | LIPGLPLKEAP1NFE2L2 | |
| SCHEMBL23294299 | 0.71 | FFAR1 (0.35) | DGAT1 | |
| SCHEMBL23294656 | 0.71 | LIPG (0.36) | LIPGLPLDGAT1KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025080784-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2025-04-17 | — | — | WO | disclosed |