SCHEMBL198775

SCHEMBL198775

O=S(=O)(Cl)c1cc(Br)ccc1Br

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
HSP90AA1 P07900 1/20 0.43
TLR9 Q9NR96 1/20 0.43
S100A4 P26447 1/20 0.43
EDNRB P24530 2/20 0.41
EDNRA P25101 2/20 0.41
ALDH1A1 P00352 2/20 0.41
GLA P06280 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CA2 P00918 3/20 0.38
PTPRC P08575 1/20 0.38
KMT2A Q03164 3/20 0.37
CTSL P07711 2/20 0.37
CTSS P25774 2/20 0.37
CTSK P43235 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CTSB P07858 1/20 0.37
CA1 P00915 2/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29882666 1.00 LMNA (0.44) LMNAHSP90AA1TLR9S100A4EDNRB
SCHEMBL197054 0.82 S100A4 (0.48) LMNAHSP90AA1TLR9S100A4GLA
SCHEMBL31470482 0.82 HSP90AA1 (0.43) LMNAHSP90AA1TLR9S100A4ALDH1A1
SCHEMBL1814581 0.82 HSP90AA1 (0.43) LMNAHSP90AA1TLR9S100A4ALDH1A1
SCHEMBL1326389 0.82 CA2 (0.37) LMNAALDH1A1SMN1; SMN2CA2CA1
SCHEMBL2244585 0.80 TRPV4 (0.40) LMNAS100A4ALDH1A1GLASMN1; SMN2
SCHEMBL5026196 0.80 ALDH1A1 (0.39) LMNAALDH1A1CA2KMT2AL3MBTL1
SCHEMBL8053895 0.79 CA2 (0.54) LMNAHSP90AA1TLR9S100A4EDNRB
SCHEMBL1121492 0.78 WDR5 (0.53) WDR5CA12CA9
SCHEMBL4615229 0.78 GLA (0.37) LMNAHSP90AA1TLR9S100A4GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104678028-A Pretreatment and detection method for biogen amine neurotransmitter and detection kit INST PHARM & TOXICOLOGY AMMS 2015-06-03 CN claimed
US-20250115687-A1 PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, AND CATALYST FOR POLYMERIZAING OLEFINS FORMOSA PLASTICS CORP USA (US) 2025-04-10 US disclosed
WO-2025075722-A1 PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, AND CATALYST FOR POLYMERIZAING OLEFINS FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2025-04-10 WO disclosed
US-20250084077-A1 ETHER LINKED TRIAZOLES AS NRF2 ACTIVATORS ASTEX THERAPEUTICS LIMITED (GB) 2025-03-13 US disclosed
US-12091409-B2 Ether linked triazoles as NRF2 activators ASTEX THERAPEUTICS LIMITED (GB) 2024-09-17 US disclosed
CN-117402124-A Aryl sulfonamide compound and anti-influenza application thereof 中国医学科学院医药生物技术研究所 2024-01-16 CN disclosed
EP-3311136-B1 LONG WAVELENGTH VOLTAGE SENSITIVE DYES UNIV CALIFORNIA (US) 2023-06-07 EP disclosed
US-11500247-B2 Liquid crystal sensor PLATYPUS TECHNOLOGIES, LLC (US) 2022-11-15 US disclosed
CN-111620817-B Novel blue thermal activity delayed fluorescent material and application thereof 常州大学 2022-09-27 CN disclosed
US-20220089590-A1 ETHER LINKED TRIAZOLES AS NRF2 ACTIVATORS ASTEX THERAPEUTICS LIMITED (GB) 2022-03-24 US disclosed
WO-1998001422-A1 NEW AMIDINO DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS ASTRA AKTIEBOLAG (SE) 1998-01-15 WO disclosed
EP-0511826-B1 Phosphosulfonate herbicides ROHM & HAAS (US) 1997-07-16 EP disclosed
US-5500405-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1996-03-19 US disclosed
US-5272128-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1993-12-21 US disclosed
EP-0511826-A2 Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1992-11-04 EP disclosed
US-4298384-A ALKOXYCARBONYL CHLORETHYL DIHALOPHENYL SULFONE YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD. (IL) 1981-11-03 US disclosed
US-4206235-A Novel 2,5-dihalophenyl-β-substituted sulfone fungicides YEDA RESEARCH & DEVELOPMENT CO., LTD. (IL) 1980-06-03 US disclosed
US-4178330-A Haloaryl halobenzenesulfonate flame retardants VELSICOL CHEMICAL CORPORATION (US) 1979-12-11 US disclosed
US-4163005-A FOR USE IN POLYMER COMPOSITIONS VELSICOL CHEMICAL CORPORATION (US) 1979-07-31 US disclosed
EP-0001017-A1 Haloaryl halobenzenesulfonates, their production and their use as flame retardants Velsicol Chemical Corporation (US) 1979-03-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220089590-A1 ETHER LINKED TRIAZOLES AS NRF2 ACTIVATORS NFE2L2, KEAP1, NQO1 LMNA 2478/4885HSP90AA1 1694/4885TLR9 3847/4885
US-20250084077-A1 ETHER LINKED TRIAZOLES AS NRF2 ACTIVATORS NFE2L2, KEAP1, NQO1 LMNA 2478/4885HSP90AA1 1694/4885TLR9 3847/4885
US-12091409-B2 Ether linked triazoles as NRF2 activators NFE2L2, KEAP1, NQO1 LMNA 2478/4885HSP90AA1 1694/4885TLR9 3847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.