SCHEMBL3147164

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3142474	0.92	HTR6 (0.52)	HTR6ALDH1A1PKMMEN1KMT2A
	SCHEMBL3156832	0.90	DHCR7 (0.52)	HTR6OXTR
	SCHEMBL3153506	0.90	HTR6 (0.56)	HTR6OXTRPKMPKLR
	SCHEMBL3154029	0.89	HTR6 (0.51)	HTR6CYP2C19ALDH1A1CYP2D6MAPT
	SCHEMBL3148376	0.89	HTR6 (0.53)	HTR6CYP2C19ALDH1A1CYP2D6MAPT
	SCHEMBL3152816	0.89	HTR6 (0.49)	HTR6ALDH1A1OXTRKDM4E
	SCHEMBL3157119	0.89	EPHX2 (0.48)	HTR6MAPTSMN1; SMN2OXTRMEN1
	SCHEMBL3144660	0.89	LMNA (0.47)	HTR6ALDH1A1MAPTKDM4E
	SCHEMBL3152271	0.89	LMNA (0.54)	HTR6SMN1; SMN2KMT2A
	SCHEMBL3153657	0.88	HTR6 (0.55)	HTR6ALDH1A1SMN1; SMN2PKMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.