SCHEMBL31474178

SCHEMBL31474178

Cc1c(NC(=O)c2cc3c(cc2F)OC(C)(C)C3)cc(F)cc1B1OC(C)(C)C(C)(C)O1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
IRAK4 Q9NWZ3 19/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31474255 0.82 TP53 (0.38) ALDH1A1MAPTIRAK4
SCHEMBL31474105 0.82 ALDH1A1 (0.47) ALDH1A1MAPTIRAK4
SCHEMBL31474221 0.81 LIPE (0.32) ALDH1A1MAPT
SCHEMBL31474190 0.80 BTK (0.34) ALDH1A1MAPT
SCHEMBL31474008 0.79 NPC1 (0.33) ALDH1A1
SCHEMBL31473998 0.77 LIPE (0.36) ALDH1A1MAPT
SCHEMBL27003891 0.76 LIPE (0.39)
SCHEMBL16754856 0.76 BTK (0.45)
SCHEMBL29520132 0.76 BTK (0.45)
SCHEMBL31474086 0.76 ALDH1A1 (0.36) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025061148-A1 HETEROARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE 江苏恒瑞医药股份有限公司 2025-03-27 WO disclosed