Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 6/20 | 0.48 |
| ▸ | NOS3 | P29474 | 3/20 | 0.48 |
| ▸ | NOS1 | P29475 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11351977 | 0.86 | PPARG (0.48) | KMT2AMEN1GAACTSSCTSK | |
| SCHEMBL28384249 | 0.86 | ATM (0.46) | CTSKMAPK1ANPEPESR1ESR2 | |
| SCHEMBL433224 | 0.86 | ESR1 (0.58) | TSHRKMT2AMEN1CTSSCTSK | |
| SCHEMBL12321430 | 0.84 | CTSC (0.49) | NOS2KMT2AMAPK1ANPEPESR1 | |
| SCHEMBL11925791 | 0.84 | NLRP3 (0.47) | MAPK1ANPEPESR1ESR2 | |
| SCHEMBL10523997 | 0.84 | ANPEP (0.57) | KMT2AMEN1CTSSCTSKANPEP | |
| SCHEMBL9788997 | 0.83 | TAS1R3 (0.46) | GAAMAPK1ANPEPESR1ESR2 | |
| SCHEMBL10536462 | 0.82 | ALDH1A1 (0.47) | TSHRKMT2AMEN1GAAMAPK1 | |
| SCHEMBL21763387 | 0.82 | ANPEP (0.52) | CTSSCTSKANPEPPPARG | |
| SCHEMBL31323946 | 0.80 | CPA1 (0.47) | KMT2ACTSSCTSKPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025060978-A1 | TRICYCLIC PYRIDINE COMPOUND ACTING AS SARM1 ENZYME ACTIVITY INHIBITOR, AND USE THEREOF | 科辉智药(深圳)新药研究中心有限公司 | 2025-03-27 | — | — | WO | disclosed |