Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.58 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PDE4A | P27815 | 2/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.49 |
| ▸ | CCR1 | P32246 | 3/20 | 0.49 |
| ▸ | CCR8 | P51685 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1506959 | 0.86 | HTR1A (0.53) | HTTKMT2APDE4APDE4BPDE4C | |
| SCHEMBL13036181 | 0.85 | KMT2A (0.50) | PSMD14COPS5SLC6A2HTTKMT2A | |
| SCHEMBL1337689 | 0.85 | HTR1A (0.61) | PSMD14COPS5SLC6A2HTTHTR1A | |
| SCHEMBL27624147 | 0.82 | PSMD14 (0.54) | PSMD14COPS5SLC6A2HTTKMT2A | |
| SCHEMBL18029399 | 0.82 | PSMD14 (0.59) | PSMD14COPS5SLC6A2HTTKMT2A | |
| SCHEMBL12600028 | 0.81 | HTR1A (0.53) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24047205 | 0.81 | PSMD14 (0.53) | PSMD14COPS5SLC6A2HTTKMT2A | |
| SCHEMBL621309 | 0.80 | KMT2A (0.54) | HTTKMT2APDE4APDE4BPDE4C | |
| SCHEMBL14468392 | 0.80 | KDM4E (0.56) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL13509619 | 0.80 | PSMD14 (0.51) | PSMD14COPS5KMT2APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117645562-A | Ligand for copper catalytic coupling reaction and application thereof | 江西德璟生物科技有限公司 | 2024-03-05 | — | — | CN | disclosed |
| EP-3272880-A2 | METHOD FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF METASTATIC CANCER | Fundació Institut de Recerca Biomèdica IRB (Barcelona) (ES) | 2018-01-24 | — | — | EP | disclosed |
| US-9260555-B2 | Amphiphilic macromolecule and the purpose of this amphiphilic macromolecule | BEIJING JUNLUN RUNZHONG SCIENCE & TECHNOLOGY CO., LIMITED (CN) | 2016-02-16 | — | — | US | disclosed |
| US-9243097-B2 | Amphiphilic macromolecule and the purpose of this amphiphilic macromolecule | BEIJING JUNLUN RUNZHONG SCIENCE & TECHNOLOGY CO., LIMITED (CN) | 2016-01-26 | — | — | US | disclosed |
| US-9243097-B2 | Amphiphilic macromolecule and the purpose of this amphiphilic macromolecule | BEIJING JUNLUN RUNZHONG SCIENCE & TECHNOLOGY CO., LIMITED (CN) | 2016-01-26 | — | — | US | disclosed |
| US-20150183911-A1 | AMPHIPHILIC MACROMOLECULE AND THE PURPOSE OF THIS AMPHIPHILIC MACROMOLECULE | BEIJING JUNLUN RUNZHONG SCIENCE & TECHNOLOGY CO., LIMITED (CN) | 2015-07-02 | — | — | US | disclosed |
| US-20140350204-A1 | AMPHIPHILIC MACROMOLECULE AND THE PURPOSE OF THIS AMPHIPHILIC MACROMOLECULE | BEIJING JUNLUN RUNZHONG SCIENCE & TECHNOLOGY CO., LTD. (CN) | 2014-11-27 | — | — | US | disclosed |
| US-20140350204-A1 | AMPHIPHILIC MACROMOLECULE AND THE PURPOSE OF THIS AMPHIPHILIC MACROMOLECULE | BEIJING JUNLUN RUNZHONG SCIENCE & TECHNOLOGY CO., LTD. (CN) | 2014-11-27 | — | — | US | disclosed |
| EP-2233493-A1 | Macrolides | Pfizer Products Inc. (US) | 2010-09-29 | — | — | EP | disclosed |
| EP-1836211-B1 | MACROLIDES | PFIZER PROD INC (US) | 2010-03-03 | — | — | EP | disclosed |
| US-7641820-B2 | Nano compounds and organic memory devices comprising the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2010-01-05 | — | — | US | disclosed |
| US-7462600-B2 | Macrolides | PFIZER INC (US) | 2008-12-09 | — | — | US | disclosed |
| US-20060135447-A1 | Macrolides | CHUPAK LOUIS S | 2006-06-22 | — | — | US | disclosed |
| US-20050010048-A1 | Aza-and polyaza-naphthalenly ketones useful as hiv integrase inhibitors | ZHUANG LINGHANG (US) | 2005-01-13 | — | — | US | disclosed |
| EP-1333831-A2 | AZA-AND POLYAZA-NAPHTHALENYL KETONES USEFUL AS HIV INTEGRASE INHIBITORS | Merck & Co., Inc. (US) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002036734-A2 | AZA-AND POLYAZA-NAPHTHALENYL KETONES USEFUL AS HIV INTEGRASE INHIBITORS | MERCK & CO., INC. (US) | 2002-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135447-A1 | Macrolides | LCAT, NOP2, HDAC6 | PSMD14 2531/4885COPS5 2054/4885SLC6A2 3752/4885 |
| US-20050010048-A1 | Aza-and polyaza-naphthalenly ketones useful as hiv integrase inhibitors | POLI, CYP51A1, DUT | PSMD14 1987/4885COPS5 3378/4885SLC6A2 3605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.