Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060612 | 0.79 | SMN1; SMN2 (0.45) | ALDH1A1KMT2ATAS1R3TAS1R1SMN1; SMN2 | |
| SCHEMBL3147639 | 0.76 | GRM1 (0.40) | ALDH1A1KMT2ASMN1; SMN2MEN1NPSR1 | |
| SCHEMBL25449776 | 0.72 | ALDH1A1 (0.55) | ALDH1A1KMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL9645630 | 0.72 | ALDH1A1 (0.40) | ALDH1A1KMT2ATAS1R3TAS1R1TSHR | |
| SCHEMBL4062797 | 0.72 | ALDH1A1 (0.49) | ALDH1A1KMT2ATAS1R3TAS1R1TSHR | |
| SCHEMBL8794058 | 0.71 | TAS1R3 (0.39) | ALDH1A1KMT2ATAS1R3TAS1R1TSHR | |
| SCHEMBL9645239 | 0.71 | ALOX5 (0.46) | ALDH1A1KMT2ATSHRMAPK1SMN1; SMN2 | |
| Acetic Acid Methyl Ester SCHEMBL11748064 | 0.69 | ALDH1A1 (0.59) | ALDH1A1LMNACA12CA1CA2 | |
| Acetic Acid Methyl Ester SCHEMBL27516763 | 0.69 | ALDH1A1 (0.59) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL31219787 | 0.69 | ALDH1A1 (0.55) | ALDH1A1KMT2ARECQLSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256158-B2 | 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides | BAYER AG (DE) | 2007-08-14 | — | — | US | disclosed |
| US-7256158-B2 | 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides | BAYER AG (DE) | 2007-08-14 | — | — | US | disclosed |
| US-7256158-B2 | 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides | BAYER AG (DE) | 2007-08-14 | — | — | US | disclosed |
| US-6933261-B2 | 2,4,5-Trisubstituted phenylketoenols | BAYER AKTIENGESELLSCHAFT (DE) | 2005-08-23 | — | — | US | disclosed |
| US-20050038021-A1 | 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides | BAYER AG (DE) | 2005-02-17 | — | — | US | disclosed |
| US-20030171219-A1 | 2,4,5-trisubstituted phenylketo-enols for use as pesticides and herbicides | LIEB FOLKER (DE) | 2003-09-11 | — | — | US | disclosed |
| US-6511942-B1 | Animal husbandry, veterinary medicine | BAYER AKTIENGESELLSCHAFT (DE) | 2003-01-28 | — | — | US | disclosed |
| EP-0837847-B1 | 2,4,5-TRISUBSTITUTED PHENYLKETO-ENOLS FOR USE AS PESTICIDES AND HERBICIDES | BAYER AG (DE) | 2002-09-18 | — | — | EP | disclosed |
| US-6110872-A | 3-(2,4,5-TRISUBSTITUTED PHENYL), 4-HYDROXY,5,5-(CYCLOALKYL OR HETEROCYCLOALKYL)PYRROLIN-2-ONE AND DERIVATIVES; METHOD OF MAKING BY INTRAMOLECULAR CONDENSATION OF SPECIFIED COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 2000-08-29 | — | — | US | disclosed |
| EP-0837847-A1 | 2,4,5-TRISUBSTITUTED PHENYLKETO-ENOLS FOR USE AS PESTICIDES AND HERBICIDES | BAYER AG (DE) | 1998-04-29 | — | — | EP | disclosed |
| WO-1997001535-A1 | 2,4,5-TRISUBSTITUTED PHENYLKETO-ENOLS FOR USE AS PESTICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038021-A1 | 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides | DDT, CYP4X1, PDHX | ALDH1A1 1592/4885KMT2A 409/4885TAS1R3 4115/4885 |
| US-20030171219-A1 | 2,4,5-trisubstituted phenylketo-enols for use as pesticides and herbicides | DDT, CYP4X1, HPD | ALDH1A1 855/4885KMT2A 494/4885TAS1R3 4165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.